Deficiency of neural recognition molecule NB-2 affects the development of glutamatergic auditory pathways from the ventral cochlear nucleus to the superior olivary complex in mouse

Neural recognition molecule NB-2/contactin 5 is expressed transiently during the first postnatal week in glutamatergic neurons of the central auditory system. Here, we investigated the effect of NB-2 deficiency on the auditory brainstem in mouse. While almost all principal neurons are wrapped with t...

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Veröffentlicht in:	Developmental biology 2009-12, Vol.336 (2), p.192-200
Hauptverfasser:	Toyoshima, Manabu, Sakurai, Kunie, Shimazaki, Kuniko, Takeda, Yasuo, Shimoda, Yasushi, Watanabe, Kazutada
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Apoptosis Auditory brainstem Auditory brainstem response Auditory Pathways Bushy neuron Calyx of Held Cell adhesion molecule Cell Adhesion Molecules, Neuronal - genetics Cell Adhesion Molecules, Neuronal - immunology Cell Adhesion Molecules, Neuronal - physiology Cochlear Nucleus - embryology Contactin Glutamatergic neuron Glutamates - metabolism In Situ Hybridization Mice Mice, Inbred C57BL Mice, Knockout Neurons - cytology Olivary Nucleus - embryology Postnatal development Synapse formation
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