Needle-Free Subcutaneous Sumatriptan (Sumavel™ DosePro™): Bioequivalence and Ease of Use

Background.— Subcutaneous (s.c.) injection of sumatriptan is currently associated with needle aversion in some patients, and sharps disposal issues. Objectives.— To investigate whether a needle‐free system can deliver s.c. sumatriptan. If so, to examine whether needle‐free administration is bioequiv...

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Veröffentlicht in:	Headache 2009-11, Vol.49 (10), p.1435-1444
Hauptverfasser:	Brandes, Jan Lewis, Cady, Roger K., Freitag, Fred G., Smith, Timothy R., Chandler, Patricia, Fox, Anthony W., Linn, Lawrence, Farr, Stephen J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult bioequivalence Biological and medical sciences Cardiovascular system clinical utility Cross-Over Studies Drug Delivery Systems - methods Drug Delivery Systems - utilization Female Humans Injections, Subcutaneous Male Medical sciences Middle Aged Migraine Disorders - drug therapy Migraine Disorders - metabolism needle-free administration Needles Neurology pharmacokinetic Pharmacology. Drug treatments Prospective Studies subcutaneous sumatriptan Sumatriptan - administration & dosage Sumatriptan - pharmacokinetics Therapeutic Equivalency Vascular diseases and vascular malformations of the nervous system Vasodilator agents. Cerebral vasodilators
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