In Vivo Physiological Transdifferentiation of Adult Adipose Cells

Grafts of adipose tissue from adult Rosa26 mice from different sites of the body, irrespective of the sex of the donor, share with the mammary fat the property of giving rise to milk‐secreting epithelial cells when exposed to the microenvironment of the mammary gland in pregnant and lactating female...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2009-11, Vol.27 (11), p.2761-2768
Hauptverfasser:	De Matteis, Rita, Zingaretti, Marcia Cristina, Murano, Incoronata, Vitali, Alessandra, Frontini, Andrea, Giannulis, Ioanis, Barbatelli, Giorgio, Marcucci, Francesco, Bordicchia, Marica, Sarzani, Riccardo, Raviola, Elio, Cinti, Saverio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - metabolism Adipocytes - ultrastructure Adipose Tissue, White - cytology Animals Antigens, CD34 - genetics Cell Differentiation - physiology Cell Transdifferentiation Female Immunohistochemistry Kruppel-Like Transcription Factors - genetics Lactation - physiology Leukocyte Common Antigens - genetics Male Mammary epithelial cell Mammary Glands, Animal - cytology Mammary Glands, Animal - metabolism Mammary Glands, Animal - ultrastructure Mice Microscopy, Electron, Transmission Octamer Transcription Factor-3 - genetics Polymerase Chain Reaction Pregnancy Proto-Oncogene Proteins c-myc - genetics Reprogrammation SOXB1 Transcription Factors - genetics Stem Cells - metabolism Thy-1 Antigens - genetics Transcription Factors - genetics Transcription Factors - metabolism Transdifferentiation White adipocytes White adipose tissue
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