MMP-2 and MMP-9 Alteration in Response to Collaring in Rabbits: The Effects of Endothelin Receptor Antagonism

Matrix metalloproteinases (MMPs), and, in particular, gelatinases (MMP-2 and MMP-9), have been implicated in vascular cell proliferation and/or migration, contributing to intimal thickening, an essential stage in the development of atherosclerosis and restenosis following balloon angioplasty. Endoth...

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Veröffentlicht in:	Journal of cardiovascular pharmacology and therapeutics 2009-12, Vol.14 (4), p.292-301
Hauptverfasser:	Reel, Buket, Oktay, Gulgun, Ozkal, Sermin, Islekel, Huray, Ozer, Erdener, Ozsarlak-Sozer, Gonen, Cavdar, Zahide, Akhisaroglu, Serpil Tanriverdi, Kerry, Zeliha
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carotid Arteries - drug effects Carotid Arteries - enzymology Coronary Artery Disease - enzymology Coronary Artery Disease - etiology Coronary Artery Disease - metabolism Disease Models, Animal Endothelin Receptor Antagonists Enzyme Activation - drug effects Enzyme Precursors - metabolism Female Gelatinases - metabolism Male Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Peptides, Cyclic - pharmacology Rabbits Tunica Intima - anatomy & histology Tunica Intima - cytology Tunica Intima - drug effects Tunica Intima - metabolism
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