Autoimmune Polyglandular Syndrome Type 2 With Myasthenia Gravis Crisis
We describe a rare case of autoimmune polyglandular syndrome type 2 initially presenting as Addison disease and autoimmune thyroid disease, with subsequent development of autoimmune hepatitis and myasthenia gravis (MG) crisis in a Japanese woman. MG improved with oral prednisolone followed by plasma...
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| Veröffentlicht in: | The Neurologist (Baltimore, Md.) Md.), 2009-11, Vol.15 (6), p.361-363 |
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| container_issue | 6 |
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| container_title | The Neurologist (Baltimore, Md.) |
| container_volume | 15 |
| creator | Konno, Shingo Ichijo, Takamasa Murata, Mayumi Toda, Takahiro Nakazora, Hiroshi Nomoto, Nobuatsu Sugimoto, Hideki Nemoto, Hiroshi Kurihara, Teruyuki Wakata, Nobuo Fujioka, Toshiki |
| description | We describe a rare case of autoimmune polyglandular syndrome type 2 initially presenting as Addison disease and autoimmune thyroid disease, with subsequent development of autoimmune hepatitis and myasthenia gravis (MG) crisis in a Japanese woman. MG improved with oral prednisolone followed by plasmapheresis for immunoadsorption; thymectomy was not performed. Conventional treatment for MG was effective and safe in this case, in which there was positivity for human leukocyte antigen A23, B52, B62, DR11, and DR15. |
| doi_str_mv | 10.1097/NRL.0b013e3181945437 |
| format | Article |
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MG improved with oral prednisolone followed by plasmapheresis for immunoadsorption; thymectomy was not performed. 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MG improved with oral prednisolone followed by plasmapheresis for immunoadsorption; thymectomy was not performed. Conventional treatment for MG was effective and safe in this case, in which there was positivity for human leukocyte antigen A23, B52, B62, DR11, and DR15.</description><subject>Aged</subject><subject>Female</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Myasthenia Gravis - complications</subject><subject>Myasthenia Gravis - drug therapy</subject><subject>Myasthenia Gravis - surgery</subject><subject>Plasmapheresis - methods</subject><subject>Polyendocrinopathies, Autoimmune - complications</subject><subject>Polyendocrinopathies, Autoimmune - drug therapy</subject><subject>Polyendocrinopathies, Autoimmune - surgery</subject><subject>Prednisolone - therapeutic use</subject><subject>Thymectomy - methods</subject><issn>1074-7931</issn><issn>2331-2637</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE9r20AQxZfSkjhOvkEpuvWkZGZ3pdUcg6ndgJuE_CHHZS3N1moly92VGvTtqxKDIQPDXN578_gJ8RnhEoHM1e3D-hI2gIoVFkg608p8EDOpFKYyV-ajmCEYnRpSeCrOYvwFgJRLfSJOkQjQSJyJ5fXQd3XbDjtO7rtm_Nm4XTU0LiSP464KXcvJ07jnRCYvdb9Nfowu9lve1S5ZBfe3jski1LGO5-KTd03ki8Odi-flt6fF93R9t7pZXK_TUmWYp1piKRE2pE1JlOmiIkkeMZNgKiKjDE0jM-8LCdrJ3FcVar9h5zkrPau5-PqWuw_dn4Fjb9s6ltxMrbkbojVKo5Kaikmp35Rl6GIM7O0-1K0Lo0Ww_wHaCaB9D3CyfTk8GDYtV0fTgdgx97Vreg7xdzO8crBbdk2_tRNiaQpSqQQgRABIp8Vc_QP5U3r1</recordid><startdate>200911</startdate><enddate>200911</enddate><creator>Konno, Shingo</creator><creator>Ichijo, Takamasa</creator><creator>Murata, Mayumi</creator><creator>Toda, Takahiro</creator><creator>Nakazora, Hiroshi</creator><creator>Nomoto, Nobuatsu</creator><creator>Sugimoto, Hideki</creator><creator>Nemoto, Hiroshi</creator><creator>Kurihara, Teruyuki</creator><creator>Wakata, Nobuo</creator><creator>Fujioka, Toshiki</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200911</creationdate><title>Autoimmune Polyglandular Syndrome Type 2 With Myasthenia Gravis Crisis</title><author>Konno, Shingo ; 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| fulltext | fulltext |
| identifier | ISSN: 1074-7931 |
| ispartof | The Neurologist (Baltimore, Md.), 2009-11, Vol.15 (6), p.361-363 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Aged Female Glucocorticoids - therapeutic use Humans Myasthenia Gravis - complications Myasthenia Gravis - drug therapy Myasthenia Gravis - surgery Plasmapheresis - methods Polyendocrinopathies, Autoimmune - complications Polyendocrinopathies, Autoimmune - drug therapy Polyendocrinopathies, Autoimmune - surgery Prednisolone - therapeutic use Thymectomy - methods |
| title | Autoimmune Polyglandular Syndrome Type 2 With Myasthenia Gravis Crisis |
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