Endothelium-dependent vasorelaxant effects of the essential oil from aerial parts of Alpinia zerumbet and its main constituent 1,8-cineole in rats

Vasorelaxant effects of essential oil of Alpinia zerumbet (EOAZ) and its main constituent, 1,8-cineole (CIN) were studied. In rat isolated aorta preparations with intact endothelium, EOAZ (0.01–3000 μg/ml) induced significant but incomplete relaxation of the phenylephrine-induced contraction, an eff...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2009-12, Vol.16 (12), p.1151-1155
Hauptverfasser:	Pinto, Nilson V., Assreuy, Ana Maria S., Coelho-de-Souza, Andrelina N., Ceccatto, Vania M., Magalhães, Pedro Jorge C., Lahlou, Saad, Leal-Cardoso, José Henrique
Format:	Artikel
Sprache:	eng
Schlagworte:	1,8-Cineole Alpinia - chemistry Alpinia zerumbet Animals Aorta Cardiovascular Agents - pharmacology Chemical properties Cyclohexanols - pharmacology Endothelium, Vascular - drug effects Essences and essential oils Essential oil Galangal Health aspects Indomethacin - pharmacology Isolated thoracic aorta Male Monoterpenes - pharmacology NG-Nitroarginine Methyl Ester - pharmacology Nitric oxide Oils, Volatile - pharmacology Phenylephrine Physiological aspects Plant Components, Aerial Plant Extracts - pharmacology Plant Leaves Rats Rattus Tetraethylammonium - pharmacology Vasoconstriction - drug effects Vasodilation - drug effects Vasodilator Agents - pharmacology
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