Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

Arachidonylethanolamide, an arachidonic acid derivative in porcine brain, was identified in a screen for endogenous ligands for the cannabinoid receptor. The structure of this compound, which has been named "anandamide," was determined by mass spectrometry and nuclear magnetic resonance sp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1992-12, Vol.258 (5090), p.1946-1949
Hauptverfasser:	Devane, William A., Hanuš, Lumir, Breuer, Aviva, Pertwee, Roger G., Stevenson, Lesley A., Griffin, Graeme, Gibson, Dan, Mandelbaum, Asher, Etinger, Alexander, Mechoulam, Raphael
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - chemistry Amides - isolation & purification Amides - pharmacology anandamide Animals Arachidonic Acids arachidonylethanolamide Binding, Competitive Biological and medical sciences Brain - metabolism Brain Chemistry Cannabinoid receptors Cannabinoids Cannabinoids - metabolism characterization Chromatography, Thin Layer Dehydration Drug addictions Drug receptors Endocannabinoids endogenous Fatty acids Fatty Acids, Unsaturated - chemistry Fatty Acids, Unsaturated - isolation & purification Fatty Acids, Unsaturated - pharmacology Gas Chromatography-Mass Spectrometry Ions Kinetics Ligands Mass spectroscopy Medical sciences Physiological aspects pigs Polyunsaturated Alkamides Protons Receptors Receptors, Cannabinoid Receptors, Drug - metabolism Swine Toxicology Vas deferens
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!