The CD163-expressing macrophages recognize and internalize TWEAK Potential consequences in atherosclerosis

CD163 is a new potential scavenger receptor of Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) which elicits diverse biologic actions involved in atherosclerosis. We have analyzed the importance of TWEAK-CD163 interaction in atherosclerosis. TWEAK and CD163 interaction was studied in cu...

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Veröffentlicht in:	Atherosclerosis 2009-11, Vol.207 (1), p.103-110
Hauptverfasser:	MORENO, Juan A, MUNOZ-GARCIA, Begoña, MARTIN-VENTURA, Jose L, MADRIGAL-MATUTE, Julio, ORBE, Josune, PARAMO, Jose A, ORTEGA, Luis, EGIDO, Jesús, BLANCO-COLIO, Luis M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens, CD - blood Antigens, CD - genetics Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - blood Antigens, Differentiation, Myelomonocytic - genetics Antigens, Differentiation, Myelomonocytic - metabolism Atherosclerosis (general aspects, experimental research) Biological and medical sciences Biological Transport Biomarkers - blood Blood and lymphatic vessels Cardiology. Vascular system Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - immunology Carotid Artery Diseases - metabolism Carotid Artery Diseases - surgery Cell Line Cytokine TWEAK Endarterectomy, Carotid Enzyme-Linked Immunosorbent Assay Female Humans Immunohistochemistry Macrophages - immunology Macrophages - metabolism Male Medical sciences Middle Aged Receptors, Cell Surface - blood Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism RNA, Messenger - metabolism Severity of Illness Index Time Factors Tobacco, tobacco smoking Toxicology Tumor Necrosis Factors - blood Tumor Necrosis Factors - genetics Tumor Necrosis Factors - metabolism Ultrasonography
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