A Novel Ultrasound Microbubble Carrying Gene and Tat Peptide: Preparation and Characterization

Rationale and Objectives Ultrasound-targeted microbubble destruction is a promising technology for the targeted gene delivery. The purpose of the present study is to prepare a novel lipid ultrasound microbubble-carrying gene and transactivating transcriptional activator (Tat) peptide and to investig...

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Veröffentlicht in:	Academic radiology 2009-12, Vol.16 (12), p.1457-1465
Hauptverfasser:	Ren, Jian Li, MD, Xu, Chuan Shan, PhD, Zhou, Zhi Yi, MD, Zhang, Yong, MM, Li, Xing Sheng, MD, Zheng, Yuan Yi, MD, Ran, Hai Tao, MD, Wang, Zhi Gang, MB
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured DNA - administration & dosage DNA - genetics Endothelial Cells - metabolism gene Gene Products, tat - genetics Gene Products, tat - metabolism Gene Targeting - methods Humans Microbubble Microbubbles Radiology Sonication - methods Tat peptide Transfection - methods ultrasound contrast agent
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