Scanning the Cell Surface Proteome of Cancer Cells and Identification of Metastasis-Associated Proteins Using a Subtractive Immunization Strategy

Identification of the cell surface proteome and comparison of their expression between cells with different phenotypic characteristics is crucial to the discovery of novel cancer drug targets as well as elucidating the basic biologic processes of cancer. However, cell surface proteomics are complex...

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Veröffentlicht in:	Journal of proteome research 2009-11, Vol.8 (11), p.5048-5059
Hauptverfasser:	Rasmussen, Nicolaj, Ditzel, Henrik J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Breast Neoplasms - immunology Breast Neoplasms - pathology Cell Line, Tumor Female HLA-DR Antigens - immunology Immunization - methods Male Mice Mice, Nude Mice, SCID Neoplasm Invasiveness - physiopathology Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasms - metabolism Neoplasms - pathology Proteome - analysis Tissue Distribution
Online-Zugang:	Volltext
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