Newly detected glucose disturbance is associated with a high prevalence of diastolic dysfunction: double risk for the development of heart failure?
Diastolic dysfunction is associated with a high rate of morbidity and mortality and has a high prevalence in patients with diabetes. Aim of the study was to investigate the prevalence of diastolic dysfunction in patients with newly detected glucose metabolism disorder (GMD) submitted for coronary an...
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| Veröffentlicht in: | Acta diabetologica 2009-12, Vol.46 (4), p.335-338 |
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| container_title | Acta diabetologica |
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| creator | Füth, R. Dinh, W. Bansemir, L. Ziegler, G. Bufe, A. Wolfertz, J. Scheffold, T. Lankisch, Mark |
| description | Diastolic dysfunction is associated with a high rate of morbidity and mortality and has a high prevalence in patients with diabetes. Aim of the study was to investigate the prevalence of diastolic dysfunction in patients with newly detected glucose metabolism disorder (GMD) submitted for coronary angiography. Oral glucose tolerance test, echocardiography, and tissue Doppler imaging were performed in patients referred to coronary angiography. Prevalence of diastolic dysfunction was 97, 88, and 74% in the known diabetes, newly detected diabetes, and new diagnosed impaired glucose toleranc group, respectively. This is higher than previously reported. Severity of diastolic dysfunction was associated with higher 2-h plasma glucose levels and with new diagnosed diabetes. Screening patients with newly detected GMD for diastolic dysfunction may identify patients with double risk for cardiovascular morbidity and mortality and this group might be a target population to avoid development heart failure. |
| doi_str_mv | 10.1007/s00592-009-0105-8 |
| format | Article |
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Aim of the study was to investigate the prevalence of diastolic dysfunction in patients with newly detected glucose metabolism disorder (GMD) submitted for coronary angiography. Oral glucose tolerance test, echocardiography, and tissue Doppler imaging were performed in patients referred to coronary angiography. Prevalence of diastolic dysfunction was 97, 88, and 74% in the known diabetes, newly detected diabetes, and new diagnosed impaired glucose toleranc group, respectively. This is higher than previously reported. Severity of diastolic dysfunction was associated with higher 2-h plasma glucose levels and with new diagnosed diabetes. 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Aim of the study was to investigate the prevalence of diastolic dysfunction in patients with newly detected glucose metabolism disorder (GMD) submitted for coronary angiography. Oral glucose tolerance test, echocardiography, and tissue Doppler imaging were performed in patients referred to coronary angiography. Prevalence of diastolic dysfunction was 97, 88, and 74% in the known diabetes, newly detected diabetes, and new diagnosed impaired glucose toleranc group, respectively. This is higher than previously reported. Severity of diastolic dysfunction was associated with higher 2-h plasma glucose levels and with new diagnosed diabetes. Screening patients with newly detected GMD for diastolic dysfunction may identify patients with double risk for cardiovascular morbidity and mortality and this group might be a target population to avoid development heart failure.</abstract><cop>Milan</cop><pub>Springer Milan</pub><pmid>19277455</pmid><doi>10.1007/s00592-009-0105-8</doi><tpages>4</tpages></addata></record> |
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| ispartof | Acta diabetologica, 2009-12, Vol.46 (4), p.335-338 |
| issn | 0940-5429 1432-5233 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Aged Blood Glucose Cardiovascular disease Diabetes Diastole Female Glucose Glucose Metabolism Disorders - complications Glucose Metabolism Disorders - diagnosis Glucose Tolerance Test Heart failure Heart Failure - epidemiology Heart Failure - etiology Heart Failure - metabolism Heart Failure - physiopathology Humans Internal Medicine Male Medicine Medicine & Public Health Metabolic Diseases Metabolism Middle Aged Prevalence Risk Factors Short Communication |
| title | Newly detected glucose disturbance is associated with a high prevalence of diastolic dysfunction: double risk for the development of heart failure? |
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