The synthesis of chitosan-based silver nanoparticles and their antibacterial activity

Chitosan-based silver nanoparticles were synthesized by reducing silver nitrate salts with nontoxic and biodegradable chitosan. The silver nanoparticles thus obtained showed highly potent antibacterial activity toward both Gram-positive and Gram-negative bacteria, comparable with the highly active p...

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Veröffentlicht in:Carbohydrate research 2009-11, Vol.344 (17), p.2375-2382
Hauptverfasser: Wei, Dongwei, Sun, Wuyong, Qian, Weiping, Ye, Yongzhong, Ma, Xiaoyuan
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container_issue 17
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container_title Carbohydrate research
container_volume 344
creator Wei, Dongwei
Sun, Wuyong
Qian, Weiping
Ye, Yongzhong
Ma, Xiaoyuan
description Chitosan-based silver nanoparticles were synthesized by reducing silver nitrate salts with nontoxic and biodegradable chitosan. The silver nanoparticles thus obtained showed highly potent antibacterial activity toward both Gram-positive and Gram-negative bacteria, comparable with the highly active precursor silver salts. Silver-impregnated chitosan films were formed from the starting materials composed of silver nitrate and chitosan via thermal treatment. Compared with pure chitosan films, chitosan films with silver showed both fast and long-lasting antibacterial effectiveness against Escherichia coli. The silver antibacterial materials prepared in our present system are promising candidates for a wide range of biomedical and general applications.
doi_str_mv 10.1016/j.carres.2009.09.001
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subjects Anti-Bacterial Agents - pharmacology
Antibacterial activity
Chitosan
Chitosan - chemical synthesis
Chitosan - chemistry
Chitosan - pharmacology
Chitosan-based silver nanoparticles
Escherichia coli - drug effects
Gram-Positive Bacteria - drug effects
Metal Nanoparticles - chemistry
Microbial Sensitivity Tests
Silver
Silver nanoparticles
title The synthesis of chitosan-based silver nanoparticles and their antibacterial activity
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