Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites
Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without ascites, and to elucidate the value of body water analysis for predicting the d...
Gespeichert in:
| Veröffentlicht in: | Hepatology research 2009-11, Vol.39 (11), p.1072-1079 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1079 |
|---|---|
| container_issue | 11 |
| container_start_page | 1072 |
| container_title | Hepatology research |
| container_volume | 39 |
| creator | Hara, Nagisa Iwasa, Motoh Iwata, Kazuko Miyachi, Hirohide Tanaka, Hideaki Takeo, Masaki Fujita, Naoki Kobayashi, Yoshinao Takei, Yoshiyuki |
| description | Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without ascites, and to elucidate the value of body water analysis for predicting the development of ascites.
Methods: A total of 109 cirrhotic patients, with and without ascites, and 65 controls were studied. Intra‐ and extracellular water (ECW) in the whole body and in the arm, leg and trunk were measured using the recently developed 8‐electrodes multiple‐frequency bioelectrical impedance analyzer. Furthermore, patients without ascites were followed to an episode of ascites or death.
Results: Patients with liver cirrhosis had significantly higher ECW ratios than controls. ECW ratios were increased in cirrhotic patients with moderate and severe disease. The ECW ratio of the trunk showed highly significant changes in cirrhotic patients with ascites. The ECW ratio correlated with age, serum albumin, and prothrombin time. A relative expansion of ECW and low albumin were predictive of further episodes of ascites (log‐rank 6.94, P |
| doi_str_mv | 10.1111/j.1872-034X.2009.00546.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_734117989</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>734117989</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5096-b757e678be767e058511673b2d805a84c6be249b9435aa44a531822c1bd143ec3</originalsourceid><addsrcrecordid>eNqNkMtuEzEYhS1ERUvhFZB3rGbw3Z4FC4hKL6raCnFTNpbH80dxmGSC7VHSt8fTRGWLNz6yz_db_hDClNS0rA-rmhrNKsLFr5oR0tSESKHq_Qt09nzxsmRuVKW4UKfodUorQqgmTLxCp7RRtGFSn6Huh-tHwMMC5yVg2OfoPPT92LuIdy5DxNHlMODFELFLCVJawyZPfR9iXA45eLwtjXKY8C7kJXab7ikMYy6EDxnSG3SycH2Ct8f9HH3_cvFtdlXd3l9ezz7dVl6SRlWtlhqUNi1opYFIIylVmresM0Q6I7xqgYmmbQSXzgnhJKeGMU_bjgoOnp-j94e52zj8GSFluw5p-o7bwDAmq7mgVDemKU1zaPo4pBRhYbcxrF18tJTYSbFd2cmknUzaSbF9Umz3BX13fGRs19D9A49OS-HjobALPTz-92B7dfHwtaTCVwc-pAz7Z97F37bY0NL-vLu0n2dzNp-zG2v4X_hmmrE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>734117989</pqid></control><display><type>article</type><title>Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Hara, Nagisa ; Iwasa, Motoh ; Iwata, Kazuko ; Miyachi, Hirohide ; Tanaka, Hideaki ; Takeo, Masaki ; Fujita, Naoki ; Kobayashi, Yoshinao ; Takei, Yoshiyuki</creator><creatorcontrib>Hara, Nagisa ; Iwasa, Motoh ; Iwata, Kazuko ; Miyachi, Hirohide ; Tanaka, Hideaki ; Takeo, Masaki ; Fujita, Naoki ; Kobayashi, Yoshinao ; Takei, Yoshiyuki</creatorcontrib><description>Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without ascites, and to elucidate the value of body water analysis for predicting the development of ascites.
Methods: A total of 109 cirrhotic patients, with and without ascites, and 65 controls were studied. Intra‐ and extracellular water (ECW) in the whole body and in the arm, leg and trunk were measured using the recently developed 8‐electrodes multiple‐frequency bioelectrical impedance analyzer. Furthermore, patients without ascites were followed to an episode of ascites or death.
Results: Patients with liver cirrhosis had significantly higher ECW ratios than controls. ECW ratios were increased in cirrhotic patients with moderate and severe disease. The ECW ratio of the trunk showed highly significant changes in cirrhotic patients with ascites. The ECW ratio correlated with age, serum albumin, and prothrombin time. A relative expansion of ECW and low albumin were predictive of further episodes of ascites (log‐rank 6.94, P < 0.01). In multivariate analysis, the ECW ratio was independently associated with the development of ascites.
Conclusion: Liver cirrhosis was characterized by a redistribution of body water. The ECW ratio is a reliable tool for quantification of redistribution of body water and can predict the development of ascites.</description><identifier>ISSN: 1386-6346</identifier><identifier>EISSN: 1872-034X</identifier><identifier>DOI: 10.1111/j.1872-034X.2009.00546.x</identifier><identifier>PMID: 19619257</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Publishing Asia</publisher><subject>ascites ; bioelectrical impedance analysis ; extracellular water ; intracellular body water ; liver cirrhosis ; total body water</subject><ispartof>Hepatology research, 2009-11, Vol.39 (11), p.1072-1079</ispartof><rights>2009 The Japan Society of Hepatology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5096-b757e678be767e058511673b2d805a84c6be249b9435aa44a531822c1bd143ec3</citedby><cites>FETCH-LOGICAL-c5096-b757e678be767e058511673b2d805a84c6be249b9435aa44a531822c1bd143ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1872-034X.2009.00546.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1872-034X.2009.00546.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19619257$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hara, Nagisa</creatorcontrib><creatorcontrib>Iwasa, Motoh</creatorcontrib><creatorcontrib>Iwata, Kazuko</creatorcontrib><creatorcontrib>Miyachi, Hirohide</creatorcontrib><creatorcontrib>Tanaka, Hideaki</creatorcontrib><creatorcontrib>Takeo, Masaki</creatorcontrib><creatorcontrib>Fujita, Naoki</creatorcontrib><creatorcontrib>Kobayashi, Yoshinao</creatorcontrib><creatorcontrib>Takei, Yoshiyuki</creatorcontrib><title>Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites</title><title>Hepatology research</title><addtitle>Hepatol Res</addtitle><description>Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without ascites, and to elucidate the value of body water analysis for predicting the development of ascites.
Methods: A total of 109 cirrhotic patients, with and without ascites, and 65 controls were studied. Intra‐ and extracellular water (ECW) in the whole body and in the arm, leg and trunk were measured using the recently developed 8‐electrodes multiple‐frequency bioelectrical impedance analyzer. Furthermore, patients without ascites were followed to an episode of ascites or death.
Results: Patients with liver cirrhosis had significantly higher ECW ratios than controls. ECW ratios were increased in cirrhotic patients with moderate and severe disease. The ECW ratio of the trunk showed highly significant changes in cirrhotic patients with ascites. The ECW ratio correlated with age, serum albumin, and prothrombin time. A relative expansion of ECW and low albumin were predictive of further episodes of ascites (log‐rank 6.94, P < 0.01). In multivariate analysis, the ECW ratio was independently associated with the development of ascites.
Conclusion: Liver cirrhosis was characterized by a redistribution of body water. The ECW ratio is a reliable tool for quantification of redistribution of body water and can predict the development of ascites.</description><subject>ascites</subject><subject>bioelectrical impedance analysis</subject><subject>extracellular water</subject><subject>intracellular body water</subject><subject>liver cirrhosis</subject><subject>total body water</subject><issn>1386-6346</issn><issn>1872-034X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNqNkMtuEzEYhS1ERUvhFZB3rGbw3Z4FC4hKL6raCnFTNpbH80dxmGSC7VHSt8fTRGWLNz6yz_db_hDClNS0rA-rmhrNKsLFr5oR0tSESKHq_Qt09nzxsmRuVKW4UKfodUorQqgmTLxCp7RRtGFSn6Huh-tHwMMC5yVg2OfoPPT92LuIdy5DxNHlMODFELFLCVJawyZPfR9iXA45eLwtjXKY8C7kJXab7ikMYy6EDxnSG3SycH2Ct8f9HH3_cvFtdlXd3l9ezz7dVl6SRlWtlhqUNi1opYFIIylVmresM0Q6I7xqgYmmbQSXzgnhJKeGMU_bjgoOnp-j94e52zj8GSFluw5p-o7bwDAmq7mgVDemKU1zaPo4pBRhYbcxrF18tJTYSbFd2cmknUzaSbF9Umz3BX13fGRs19D9A49OS-HjobALPTz-92B7dfHwtaTCVwc-pAz7Z97F37bY0NL-vLu0n2dzNp-zG2v4X_hmmrE</recordid><startdate>200911</startdate><enddate>200911</enddate><creator>Hara, Nagisa</creator><creator>Iwasa, Motoh</creator><creator>Iwata, Kazuko</creator><creator>Miyachi, Hirohide</creator><creator>Tanaka, Hideaki</creator><creator>Takeo, Masaki</creator><creator>Fujita, Naoki</creator><creator>Kobayashi, Yoshinao</creator><creator>Takei, Yoshiyuki</creator><general>Blackwell Publishing Asia</general><scope>BSCLL</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200911</creationdate><title>Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites</title><author>Hara, Nagisa ; Iwasa, Motoh ; Iwata, Kazuko ; Miyachi, Hirohide ; Tanaka, Hideaki ; Takeo, Masaki ; Fujita, Naoki ; Kobayashi, Yoshinao ; Takei, Yoshiyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5096-b757e678be767e058511673b2d805a84c6be249b9435aa44a531822c1bd143ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>ascites</topic><topic>bioelectrical impedance analysis</topic><topic>extracellular water</topic><topic>intracellular body water</topic><topic>liver cirrhosis</topic><topic>total body water</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hara, Nagisa</creatorcontrib><creatorcontrib>Iwasa, Motoh</creatorcontrib><creatorcontrib>Iwata, Kazuko</creatorcontrib><creatorcontrib>Miyachi, Hirohide</creatorcontrib><creatorcontrib>Tanaka, Hideaki</creatorcontrib><creatorcontrib>Takeo, Masaki</creatorcontrib><creatorcontrib>Fujita, Naoki</creatorcontrib><creatorcontrib>Kobayashi, Yoshinao</creatorcontrib><creatorcontrib>Takei, Yoshiyuki</creatorcontrib><collection>Istex</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Hepatology research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hara, Nagisa</au><au>Iwasa, Motoh</au><au>Iwata, Kazuko</au><au>Miyachi, Hirohide</au><au>Tanaka, Hideaki</au><au>Takeo, Masaki</au><au>Fujita, Naoki</au><au>Kobayashi, Yoshinao</au><au>Takei, Yoshiyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites</atitle><jtitle>Hepatology research</jtitle><addtitle>Hepatol Res</addtitle><date>2009-11</date><risdate>2009</risdate><volume>39</volume><issue>11</issue><spage>1072</spage><epage>1079</epage><pages>1072-1079</pages><issn>1386-6346</issn><eissn>1872-034X</eissn><abstract>Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without ascites, and to elucidate the value of body water analysis for predicting the development of ascites.
Methods: A total of 109 cirrhotic patients, with and without ascites, and 65 controls were studied. Intra‐ and extracellular water (ECW) in the whole body and in the arm, leg and trunk were measured using the recently developed 8‐electrodes multiple‐frequency bioelectrical impedance analyzer. Furthermore, patients without ascites were followed to an episode of ascites or death.
Results: Patients with liver cirrhosis had significantly higher ECW ratios than controls. ECW ratios were increased in cirrhotic patients with moderate and severe disease. The ECW ratio of the trunk showed highly significant changes in cirrhotic patients with ascites. The ECW ratio correlated with age, serum albumin, and prothrombin time. A relative expansion of ECW and low albumin were predictive of further episodes of ascites (log‐rank 6.94, P < 0.01). In multivariate analysis, the ECW ratio was independently associated with the development of ascites.
Conclusion: Liver cirrhosis was characterized by a redistribution of body water. The ECW ratio is a reliable tool for quantification of redistribution of body water and can predict the development of ascites.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>19619257</pmid><doi>10.1111/j.1872-034X.2009.00546.x</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1386-6346 |
| ispartof | Hepatology research, 2009-11, Vol.39 (11), p.1072-1079 |
| issn | 1386-6346 1872-034X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_734117989 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | ascites bioelectrical impedance analysis extracellular water intracellular body water liver cirrhosis total body water |
| title | Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T19%3A58%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Value%20of%20the%20extracellular%20water%20ratio%20for%20assessment%20of%20cirrhotic%20patients%20with%20and%20without%20ascites&rft.jtitle=Hepatology%20research&rft.au=Hara,%20Nagisa&rft.date=2009-11&rft.volume=39&rft.issue=11&rft.spage=1072&rft.epage=1079&rft.pages=1072-1079&rft.issn=1386-6346&rft.eissn=1872-034X&rft_id=info:doi/10.1111/j.1872-034X.2009.00546.x&rft_dat=%3Cproquest_cross%3E734117989%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=734117989&rft_id=info:pmid/19619257&rfr_iscdi=true |