Evaluation of anti-wrinkle effects of a novel cosmetic containing retinol using the guideline of the Japan Cosmetic Industry Association
Retinol is known to be effective in the treatment of sallowness, wrinkling, red blotchiness and hyperpigmented spots in aging skin. In this study, we have evaluated the anti‐wrinkle effects of a new cosmetic containing retinol. An open study was performed in 30 healthy Japanese women who had wrinkle...
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| Veröffentlicht in: | Journal of dermatology 2009-11, Vol.36 (11), p.583-586 |
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| container_title | Journal of dermatology |
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| creator | KAWADA, Akira KONISHI, Natsuko MOMMA, Tomoyuki OISO, Naoki KAWARA, Shigeru |
| description | Retinol is known to be effective in the treatment of sallowness, wrinkling, red blotchiness and hyperpigmented spots in aging skin. In this study, we have evaluated the anti‐wrinkle effects of a new cosmetic containing retinol. An open study was performed in 30 healthy Japanese women who had wrinkles at the corners of the eyes. The tested lotion, Retin‐OX+ (RoC SA, Colombes, France), was applied on wrinkles of one side of the face for 8 weeks, and not on the other site as a control. Anti‐wrinkle effects were evaluated by two methods: (i) doctors’ observation and photos based on the guideline of the Japan Cosmetic Industry Association; and (ii) the Robo Skin Analyzer. This lotion showed marked and moderate improvement in 34% of the subjects with a significant difference as compared with the control sites (P |
| doi_str_mv | 10.1111/j.1346-8138.2009.00716.x |
| format | Article |
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In this study, we have evaluated the anti‐wrinkle effects of a new cosmetic containing retinol. An open study was performed in 30 healthy Japanese women who had wrinkles at the corners of the eyes. The tested lotion, Retin‐OX+ (RoC SA, Colombes, France), was applied on wrinkles of one side of the face for 8 weeks, and not on the other site as a control. Anti‐wrinkle effects were evaluated by two methods: (i) doctors’ observation and photos based on the guideline of the Japan Cosmetic Industry Association; and (ii) the Robo Skin Analyzer. This lotion showed marked and moderate improvement in 34% of the subjects with a significant difference as compared with the control sites (P < 0.05). Moreover, the length and area decreased in the applied site more than the control site with a significant difference (P < 0.01). All the patients completed the study without significant adverse reactions. 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In this study, we have evaluated the anti‐wrinkle effects of a new cosmetic containing retinol. An open study was performed in 30 healthy Japanese women who had wrinkles at the corners of the eyes. The tested lotion, Retin‐OX+ (RoC SA, Colombes, France), was applied on wrinkles of one side of the face for 8 weeks, and not on the other site as a control. Anti‐wrinkle effects were evaluated by two methods: (i) doctors’ observation and photos based on the guideline of the Japan Cosmetic Industry Association; and (ii) the Robo Skin Analyzer. This lotion showed marked and moderate improvement in 34% of the subjects with a significant difference as compared with the control sites (P < 0.05). Moreover, the length and area decreased in the applied site more than the control site with a significant difference (P < 0.01). All the patients completed the study without significant adverse reactions. The tested lotion was well tolerated and may be an optional preparation for the treatment of wrinkles at the corner of the eyes.</description><subject>Administration, Topical</subject><subject>Adult</subject><subject>anti-wrinkle effects</subject><subject>Beauty Culture - standards</subject><subject>Consumer Product Safety</subject><subject>cosmeceutical</subject><subject>Cosmetics - administration & dosage</subject><subject>Emollients - administration & dosage</subject><subject>Esthetics</subject><subject>Female</subject><subject>Guidelines as Topic</subject><subject>Humans</subject><subject>Japan</subject><subject>Middle Aged</subject><subject>Patient Satisfaction</subject><subject>photoaging</subject><subject>Reference Values</subject><subject>retinol</subject><subject>Skin Aging - drug effects</subject><subject>Skin Aging - physiology</subject><subject>Treatment Outcome</subject><subject>Vitamin A - administration & dosage</subject><issn>0385-2407</issn><issn>1346-8138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFu1DAQhi1ERbeFV0C-cUoYx0lsS1yqZdm2VIBEJY6W40yKt15niZN29w362CS723LFF49__9-M9A8hlEHKxvNxlTKel4lkXKYZgEoBBCvT7Ssye_l4TWbAZZFkOYhTchbjCiBTBYM35JQpKSRXMCNPiwfjB9O7NtC2oSb0LnnsXLj3SLFp0PZxr9PQPqCnto1r7J0di9AbF1y4o90ohNbTIU6v_jfSu8HV6F3ACZ2Ea7Mxgc6f4atQD7HvdvQixta6_fS35KQxPuK7431Obr8sbueXyc335dX84iaxeSHLhNuKCWgAaoYMZFYxq5QwiJgXKhcCoCiVAAa1YhUYhbZSFWQgKqZMWfJz8uHQdtO1fwaMvV67aNF7E7AdohY8Z0xIyUenPDht18bYYaM3nVubbqcZ6GkLeqWnsPUUtp62oPdb0NsRfX8cMlRrrP-Bx9hHw6eD4dF53P13Y339eTEWI54ccBd73L7gprvXpeCi0L--LTX_8RO-5uWlXvK_SFKmXw</recordid><startdate>200911</startdate><enddate>200911</enddate><creator>KAWADA, Akira</creator><creator>KONISHI, Natsuko</creator><creator>MOMMA, Tomoyuki</creator><creator>OISO, Naoki</creator><creator>KAWARA, Shigeru</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200911</creationdate><title>Evaluation of anti-wrinkle effects of a novel cosmetic containing retinol using the guideline of the Japan Cosmetic Industry Association</title><author>KAWADA, Akira ; KONISHI, Natsuko ; MOMMA, Tomoyuki ; OISO, Naoki ; KAWARA, Shigeru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4586-3cb170f00d1e1082b1c997aeee459477005697010d91b0a9ecb9b0207b19a663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Administration, Topical</topic><topic>Adult</topic><topic>anti-wrinkle effects</topic><topic>Beauty Culture - standards</topic><topic>Consumer Product Safety</topic><topic>cosmeceutical</topic><topic>Cosmetics - administration & dosage</topic><topic>Emollients - administration & dosage</topic><topic>Esthetics</topic><topic>Female</topic><topic>Guidelines as Topic</topic><topic>Humans</topic><topic>Japan</topic><topic>Middle Aged</topic><topic>Patient Satisfaction</topic><topic>photoaging</topic><topic>Reference Values</topic><topic>retinol</topic><topic>Skin Aging - drug effects</topic><topic>Skin Aging - physiology</topic><topic>Treatment Outcome</topic><topic>Vitamin A - administration & dosage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KAWADA, Akira</creatorcontrib><creatorcontrib>KONISHI, Natsuko</creatorcontrib><creatorcontrib>MOMMA, Tomoyuki</creatorcontrib><creatorcontrib>OISO, Naoki</creatorcontrib><creatorcontrib>KAWARA, Shigeru</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KAWADA, Akira</au><au>KONISHI, Natsuko</au><au>MOMMA, Tomoyuki</au><au>OISO, Naoki</au><au>KAWARA, Shigeru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of anti-wrinkle effects of a novel cosmetic containing retinol using the guideline of the Japan Cosmetic Industry Association</atitle><jtitle>Journal of dermatology</jtitle><addtitle>J Dermatol</addtitle><date>2009-11</date><risdate>2009</risdate><volume>36</volume><issue>11</issue><spage>583</spage><epage>586</epage><pages>583-586</pages><issn>0385-2407</issn><eissn>1346-8138</eissn><abstract>Retinol is known to be effective in the treatment of sallowness, wrinkling, red blotchiness and hyperpigmented spots in aging skin. In this study, we have evaluated the anti‐wrinkle effects of a new cosmetic containing retinol. An open study was performed in 30 healthy Japanese women who had wrinkles at the corners of the eyes. The tested lotion, Retin‐OX+ (RoC SA, Colombes, France), was applied on wrinkles of one side of the face for 8 weeks, and not on the other site as a control. Anti‐wrinkle effects were evaluated by two methods: (i) doctors’ observation and photos based on the guideline of the Japan Cosmetic Industry Association; and (ii) the Robo Skin Analyzer. This lotion showed marked and moderate improvement in 34% of the subjects with a significant difference as compared with the control sites (P < 0.05). Moreover, the length and area decreased in the applied site more than the control site with a significant difference (P < 0.01). All the patients completed the study without significant adverse reactions. 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| ispartof | Journal of dermatology, 2009-11, Vol.36 (11), p.583-586 |
| issn | 0385-2407 1346-8138 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Administration, Topical Adult anti-wrinkle effects Beauty Culture - standards Consumer Product Safety cosmeceutical Cosmetics - administration & dosage Emollients - administration & dosage Esthetics Female Guidelines as Topic Humans Japan Middle Aged Patient Satisfaction photoaging Reference Values retinol Skin Aging - drug effects Skin Aging - physiology Treatment Outcome Vitamin A - administration & dosage |
| title | Evaluation of anti-wrinkle effects of a novel cosmetic containing retinol using the guideline of the Japan Cosmetic Industry Association |
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