Parathyroid hormone administration may modulate periodontal tissue levels of interleukin-6, matrix metalloproteinase-2 and matrix metalloproteinase-9 in experimental periodontitis

Background and Objective: Intermittent administration of the parathyroid hormone (1–34) has an anabolic effect on bone and it has been shown to reduce alveolar bone loss in experimental periodontitis models. The aim of the present study was to investigate the effect of parathyroid hormone on tissue...

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Veröffentlicht in:	Journal of periodontal research 2009-12, Vol.44 (6), p.744-750
Hauptverfasser:	Marques, M. R., Dos Santos, M. C. L. G., Da Silva, A. F., Nociti Jr, F. H., Barros, S. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - analysis Alveolar Bone Loss - pathology Alveolar Bone Loss - prevention & control Alveolar Process - pathology Animals Biological and medical sciences Biomarkers - analysis Cell Count Connective Tissue - drug effects Connective Tissue - pathology Dentistry Disease Models, Animal Down-Regulation Facial bones, jaws, teeth, parodontium: diseases, semeiology Gingiva - drug effects Gingiva - pathology inflammatory cytokines Injections, Subcutaneous Interleukin-1beta - analysis Interleukin-1beta - drug effects Interleukin-6 - analysis Isoenzymes - analysis Male Matrix Metalloproteinase 2 - analysis Matrix Metalloproteinase 2 - drug effects Matrix Metalloproteinase 9 - analysis Matrix Metalloproteinase 9 - drug effects matrix metalloproteinases Medical sciences Non tumoral diseases Osteoclasts - pathology Otorhinolaryngology. Stomatology parathyroid hormone Parathyroid Hormone - administration & dosage Parathyroid Hormone - therapeutic use periodontal disease Periodontitis - pathology Periodontitis - prevention & control Rats Rats, Wistar RNA, Messenger - analysis RNA, Messenger - drug effects Tartrate-Resistant Acid Phosphatase Time Factors
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