Carbohydrate determinant NeuAc-Galβ(1-4) of N-linked glycans modulates the antigenic activity of human immunodeficiency virus type 1 glycoprotein gp120

In the present study we investigated to what extent the peripheral carbohydrate structure of N-linked glycans influences the antigenic properties of human immunodeficiency virus type 1 glycoprotein 120 (gp120). Recombinant gp120 was purified from GMK cells infected with a recombinant vaccinia virus...

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Veröffentlicht in:	Journal of general virology 1992-12, Vol.73, p.3099-3105
Hauptverfasser:	BOLMSTEDT, A, OLOFSSON, S, SJÖGREN-JANSSON, E, JEANSSON, S, SJÖBLOM, I, ÅKERBLOM, L, HANSEN, J.-E. S, SHIU-LOK HU
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Antibodies, Monoclonal - immunology Antigenic determinants, haptens, artificial antigens Antigens Biological and medical sciences Carbohydrate Sequence Epitopes Fundamental and applied biological sciences. Psychology Fundamental immunology HIV Antigens - chemistry HIV Envelope Protein gp120 - chemistry HIV Envelope Protein gp120 - immunology HIV-1 - immunology Molecular immunology Molecular Sequence Data Recombinant Proteins - immunology Sialoglycoproteins - immunology Structure-Activity Relationship
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