Formulation and evaluation of ATP-containing liposomes including lactosylated ASGPr ligand

An original ligand (Lac-10-Chol) designed to interact with asialoglycoprotein receptors to potentially target hepatocyte was synthesised by grafting a lactose head to a cholesteryl structure, which was then included in liposomes. Preliminary formulation tests led to the selection of conventional for...

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Veröffentlicht in:	Journal of liposome research 2009-12, Vol.19 (4), p.287-300
Hauptverfasser:	Tep, Karona, Korb, Virginie, Richard, Cyrille, Escriou, Virginie, Largeau, Céline, Vincourt, Véronique, Bessodes, Michel, Guellier, Adeline, Scherman, Daniel, Cynober, Luc, Chaumeil, Jean-Claude, Dumortier, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - chemistry ASGPr ATP Cell Line Chemistry, Pharmaceutical Cholesterol - analogs & derivatives Cholesterol - chemistry DOTAP Fluorescence Humans Lac-10-chol Lactose - chemistry Life Sciences Ligands liposome Liposomes
Online-Zugang:	Volltext
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