The peroxisome proliferator-activated receptor-γ agonist, pioglitazone, inhibits fat accumulation and fibrosis in the livers of rats fed a choline-deficient, l-amino acid-defined diet

Administration of a choline-deficient, l-amino acid-defined (CDAA) diet to rats causes steatohepatitis, hepatic fibrosis, and hepatocellular carcinoma, a pathology similar to that observed in non-alcoholic steatohepatitis (NASH). The aim of this study was to evaluate if a peroxisome proliferator-act...

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Veröffentlicht in:	Hepatology research 2005-08, Vol.32 (4), p.235-242
Hauptverfasser:	Uto, Hirofumi, Nakanishi, Chihiro, Ido, Akio, Hasuike, Satoru, Kusumoto, Kazunori, Abe, Hiroo, Numata, Masatsugu, Nagata, Kenji, Hayashi, Katsuhiro, Tsubouchi, Hirohito
Format:	Artikel
Sprache:	eng
Schlagworte:	CDAA Fatty liver Hepatic fibrosis NASH PPAR-γ agonist
Online-Zugang:	Volltext
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