Langerhans cell histiocytosis revealed by painful hip: A case report
Abstract Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal...
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| Veröffentlicht in: | Joint, bone, spine : revue du rhumatisme bone, spine : revue du rhumatisme, 2009-10, Vol.76 (5), p.565-566 |
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| container_title | Joint, bone, spine : revue du rhumatisme |
| container_volume | 76 |
| creator | Sabeur, Hammami Chebil, B. Meriem Karim, B. Ameur Samir, Hadded Leila, Ghédira Chiraz, Hafsa Slaheddine, Chouchane Néji, Guediche Mohamed |
| description | Abstract Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety. |
| doi_str_mv | 10.1016/j.jbspin.2009.01.014 |
| format | Article |
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Skin biopsy should be preferred to a bone biopsy because of its safety.</description><identifier>ISSN: 1297-319X</identifier><identifier>EISSN: 1778-7254</identifier><identifier>DOI: 10.1016/j.jbspin.2009.01.014</identifier><identifier>PMID: 19767229</identifier><language>eng</language><publisher>France: Elsevier SAS</publisher><subject>Adrenal Cortex Hormones - therapeutic use ; Arthralgia ; Child ; Female ; Femur - diagnostic imaging ; Femur - pathology ; Functional Laterality ; Hip ; Hip Joint - diagnostic imaging ; Hip Joint - pathology ; Histiocytosis, Langerhans-Cell - diagnostic imaging ; Histiocytosis, Langerhans-Cell - drug therapy ; Histiocytosis, Langerhans-Cell - pathology ; Humans ; Infant ; Internal Medicine ; Langerhans cell histiocytosis ; Magnetic Resonance Imaging ; Osteosclerosis - diagnostic imaging ; Otitis - diagnosis ; Pain - etiology ; Radiography ; Rheumatology ; Treatment Outcome</subject><ispartof>Joint, bone, spine : revue du rhumatisme, 2009-10, Vol.76 (5), p.565-566</ispartof><rights>Société française de rhumatologie</rights><rights>2009 Société française de rhumatologie</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-c7d9681b4b169859df39a49d6680b288180acf639bec0c12e6a621231f6de9943</citedby><cites>FETCH-LOGICAL-c416t-c7d9681b4b169859df39a49d6680b288180acf639bec0c12e6a621231f6de9943</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jbspin.2009.01.014$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19767229$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sabeur, Hammami</creatorcontrib><creatorcontrib>Chebil, B. Meriem</creatorcontrib><creatorcontrib>Karim, B. Ameur</creatorcontrib><creatorcontrib>Samir, Hadded</creatorcontrib><creatorcontrib>Leila, Ghédira</creatorcontrib><creatorcontrib>Chiraz, Hafsa</creatorcontrib><creatorcontrib>Slaheddine, Chouchane</creatorcontrib><creatorcontrib>Néji, Guediche Mohamed</creatorcontrib><title>Langerhans cell histiocytosis revealed by painful hip: A case report</title><title>Joint, bone, spine : revue du rhumatisme</title><addtitle>Joint Bone Spine</addtitle><description>Abstract Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.</description><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Arthralgia</subject><subject>Child</subject><subject>Female</subject><subject>Femur - diagnostic imaging</subject><subject>Femur - pathology</subject><subject>Functional Laterality</subject><subject>Hip</subject><subject>Hip Joint - diagnostic imaging</subject><subject>Hip Joint - pathology</subject><subject>Histiocytosis, Langerhans-Cell - diagnostic imaging</subject><subject>Histiocytosis, Langerhans-Cell - drug therapy</subject><subject>Histiocytosis, Langerhans-Cell - pathology</subject><subject>Humans</subject><subject>Infant</subject><subject>Internal Medicine</subject><subject>Langerhans cell histiocytosis</subject><subject>Magnetic Resonance Imaging</subject><subject>Osteosclerosis - diagnostic imaging</subject><subject>Otitis - diagnosis</subject><subject>Pain - etiology</subject><subject>Radiography</subject><subject>Rheumatology</subject><subject>Treatment Outcome</subject><issn>1297-319X</issn><issn>1778-7254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1r3DAQhkVoyfc_CMW3nrzVSF7JyqEQkjYNLPTQBnITsjxu5HhtV2MH9t9HZhcKvQQGNKB35p15hrEr4CvgoL60q7aiMfQrwblZcUhRHLFT0LrMtVgXH1IujM4lmKcTdkbUcs6lWKtjdgJGKy2EOWV3G9f_wfjseso8dl32HGgKg99NAwXKIr6i67DOql02utA386IYr7ObzDvC9D8OcbpgHxvXEV4e3nP2-P3b79sf-ebn_cPtzSb3Bagp97o2qoSqqECZcm3qRhpXmFqpkleiLKHkzjdKmgo99yBQOSVASGhUjcYU8px93vcd4_B3RprsNtAytetxmMlqWUCCwXVSFnuljwNRxMaOMWxd3FngdsFnW7vHZxd8lkOKxeDTwWCutlj_KzrwSoKvewGmNV8DRks-YO-xDhH9ZOshvOfwfwPfhT54173gDqkd5tgnhBYsCcvtr-WEywXTVhxkaeQbOWeXCQ</recordid><startdate>20091001</startdate><enddate>20091001</enddate><creator>Sabeur, Hammami</creator><creator>Chebil, B. Meriem</creator><creator>Karim, B. Ameur</creator><creator>Samir, Hadded</creator><creator>Leila, Ghédira</creator><creator>Chiraz, Hafsa</creator><creator>Slaheddine, Chouchane</creator><creator>Néji, Guediche Mohamed</creator><general>Elsevier SAS</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20091001</creationdate><title>Langerhans cell histiocytosis revealed by painful hip: A case report</title><author>Sabeur, Hammami ; Chebil, B. Meriem ; Karim, B. Ameur ; Samir, Hadded ; Leila, Ghédira ; Chiraz, Hafsa ; Slaheddine, Chouchane ; Néji, Guediche Mohamed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-c7d9681b4b169859df39a49d6680b288180acf639bec0c12e6a621231f6de9943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Arthralgia</topic><topic>Child</topic><topic>Female</topic><topic>Femur - diagnostic imaging</topic><topic>Femur - pathology</topic><topic>Functional Laterality</topic><topic>Hip</topic><topic>Hip Joint - diagnostic imaging</topic><topic>Hip Joint - pathology</topic><topic>Histiocytosis, Langerhans-Cell - diagnostic imaging</topic><topic>Histiocytosis, Langerhans-Cell - drug therapy</topic><topic>Histiocytosis, Langerhans-Cell - pathology</topic><topic>Humans</topic><topic>Infant</topic><topic>Internal Medicine</topic><topic>Langerhans cell histiocytosis</topic><topic>Magnetic Resonance Imaging</topic><topic>Osteosclerosis - diagnostic imaging</topic><topic>Otitis - diagnosis</topic><topic>Pain - etiology</topic><topic>Radiography</topic><topic>Rheumatology</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sabeur, Hammami</creatorcontrib><creatorcontrib>Chebil, B. Meriem</creatorcontrib><creatorcontrib>Karim, B. Ameur</creatorcontrib><creatorcontrib>Samir, Hadded</creatorcontrib><creatorcontrib>Leila, Ghédira</creatorcontrib><creatorcontrib>Chiraz, Hafsa</creatorcontrib><creatorcontrib>Slaheddine, Chouchane</creatorcontrib><creatorcontrib>Néji, Guediche Mohamed</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Joint, bone, spine : revue du rhumatisme</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sabeur, Hammami</au><au>Chebil, B. Meriem</au><au>Karim, B. Ameur</au><au>Samir, Hadded</au><au>Leila, Ghédira</au><au>Chiraz, Hafsa</au><au>Slaheddine, Chouchane</au><au>Néji, Guediche Mohamed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Langerhans cell histiocytosis revealed by painful hip: A case report</atitle><jtitle>Joint, bone, spine : revue du rhumatisme</jtitle><addtitle>Joint Bone Spine</addtitle><date>2009-10-01</date><risdate>2009</risdate><volume>76</volume><issue>5</issue><spage>565</spage><epage>566</epage><pages>565-566</pages><issn>1297-319X</issn><eissn>1778-7254</eissn><abstract>Abstract Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.</abstract><cop>France</cop><pub>Elsevier SAS</pub><pmid>19767229</pmid><doi>10.1016/j.jbspin.2009.01.014</doi><tpages>2</tpages></addata></record> |
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| subjects | Adrenal Cortex Hormones - therapeutic use Arthralgia Child Female Femur - diagnostic imaging Femur - pathology Functional Laterality Hip Hip Joint - diagnostic imaging Hip Joint - pathology Histiocytosis, Langerhans-Cell - diagnostic imaging Histiocytosis, Langerhans-Cell - drug therapy Histiocytosis, Langerhans-Cell - pathology Humans Infant Internal Medicine Langerhans cell histiocytosis Magnetic Resonance Imaging Osteosclerosis - diagnostic imaging Otitis - diagnosis Pain - etiology Radiography Rheumatology Treatment Outcome |
| title | Langerhans cell histiocytosis revealed by painful hip: A case report |
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