Infrared Photoactivation Reduces Peptide Folding and Hydrogen-Atom Migration following ETD Tandem Mass Spectrometry

Peptides see the light: The photoactivation of peptide precursor cations during electron transfer dissociation (ETD) led to the generation of isotopic cluster peaks that more closely resembled theoretically predicted product‐ion distributions. This method should enable the application of ETD to low‐...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2009-01, Vol.48 (45), p.8526-8528
Hauptverfasser:	Ledvina, Aaron R, McAlister, Graeme C, Gardner, Myles W, Smith, Suncerae I, Madsen, James A, Schwartz, Jae C, Stafford, George C. Jr, Syka, John E.P, Brodbelt, Jennifer S, Coon, Joshua J
Format:	Artikel
Sprache:	eng
Schlagworte:	ionization of gases mass spectrometry peptides Peptides - chemistry photoactivation Photochemical Processes proteomics Tandem Mass Spectrometry - methods Ultraviolet Rays
Online-Zugang:	Volltext
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