Exercise-Induced ECG Changes in Brugada Syndrome

BACKGROUND—Ventricular arrhythmia occurrence during exercise is reported in Brugada syndrome (BrS). Accordingly, experimental studies suggest that BrS-linked SCN5A mutations reduce sodium current more at fast heart rates. Yet, the effects of exercise on the BrS ECG phenotype have not been studied. W...

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Veröffentlicht in:	Circulation. Arrhythmia and electrophysiology 2009-10, Vol.2 (5), p.531-539
Hauptverfasser:	Amin, Ahmad S, de Groot, Elisabeth A.A, Ruijter, Jan M, Wilde, Arthur A.M, Tan, Hanno L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis of Variance Biological and medical sciences Brugada Syndrome - genetics Brugada Syndrome - physiopathology Cardiac dysrhythmias Cardiology. Vascular system Case-Control Studies Chi-Square Distribution Chromatography, High Pressure Liquid Diseases of mother, fetus and pregnancy DNA Mutational Analysis Electrocardiography Exercise - physiology Genotype Gynecology. Andrology. Obstetrics Heart Heart Rate - physiology Humans Male Medical sciences Middle Aged Muscle Proteins - genetics Mutation, Missense NAV1.5 Voltage-Gated Sodium Channel Phenotype Polymerase Chain Reaction Pregnancy. Fetus. Placenta Retrospective Studies Sodium Channels - genetics
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