Vaccination of chickens with recombinant Salmonella expressing M2e and CD154 epitopes increases protection and decreases viral shedding after low pathogenic avian influenza challenge

Avian influenza (AI) is a significant public health concern and serious economic threat to the commercial poultry industry worldwide. Previous research demonstrates that antibodies against M2e confer protection against influenza challenge. Using the Red recombinase system in combination with overlap...

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Veröffentlicht in:	Poultry science 2009-11, Vol.88 (11), p.2244-2252
Hauptverfasser:	Layton, S.L, Kapczynski, D.R, Higgins, S, Higgins, J, Wolfenden, A.D, Liljebjelke, K.A, Bottje, W.G, Swayne, D, Berghman, L.R, Kwon, Y.M, Hargis, B.M, Cole, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Viral - genetics Antigens, Viral - immunology Antigens, Viral - metabolism avian influenza Chickens Epitopes - genetics Epitopes - metabolism immune response immunoglobulin G Influenza A virus Influenza in Birds - prevention & control Influenza Vaccines - immunology liver membrane proteins microbial colonization molecular sequence data neutralization tests nucleotide sequences oral administration pathogenicity polymerase chain reaction recombinant antigens recombinant vaccines Salmonella - genetics Salmonella - metabolism Salmonella enteritidis spleen strains tonsils vaccination viral antigens Virus Shedding
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