Imaging of Lipids in Spinal Cord Using Intermediate Pressure Matrix-Assisted Laser Desorption-Linear Ion Trap/Orbitrap MS

A hybrid linear ion trap/Orbitrap mass spectrometer was used to perform tandem mass spectrometry (MS/MS) experiments and high-resolution mass analysis of lipids desorbed from nerve tissue. A dramatic improvement in mass spectral resolution and a decrease in background are observed in the spectra col...

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Veröffentlicht in:Analytical chemistry (Washington) 2009-10, Vol.81 (20), p.8488-8495
Hauptverfasser: Landgraf, Rachelle R, Prieto Conaway, Maria C, Garrett, Timothy J, Stacpoole, Peter W, Yost, Richard A
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Sprache:eng
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