Residual immunity in older people against the influenza A(H1N1)--recent experience in northern Spain

The 2009 pandemic influenza A(H1N1) virus has a higher incidence in children and young adults, a pattern that has also been reported in seasonal influenza caused by the influenza A(H1N1)virus. We analysed age at infection in symptomatic patients with influenza in the Basque Country (northern Spain),...

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Veröffentlicht in:Euro surveillance : bulletin européen sur les maladies transmissibles 2009-10, Vol.14 (39)
Hauptverfasser: Pérez-Trallero, E, Piñeiro, L, Vicente, D, Montes, M, Cilla, G
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container_title Euro surveillance : bulletin européen sur les maladies transmissibles
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creator Pérez-Trallero, E
Piñeiro, L
Vicente, D
Montes, M
Cilla, G
description The 2009 pandemic influenza A(H1N1) virus has a higher incidence in children and young adults, a pattern that has also been reported in seasonal influenza caused by the influenza A(H1N1)virus. We analysed age at infection in symptomatic patients with influenza in the Basque Country (northern Spain), reported through the sentinel influenza surveillance system which monitors 2.2-2.5%of the population. Between September 1999 and August 2009,influenza A(H3N2) or seasonal influenza A(H1N1) was detected in 941 patients, and from April to August 2009, pandemic influenza A(H1N1) was detected in 112 patients. The H3/H1 seasonal influenza ratio was between 3.3 and 3.4 in the under 60 year olds,but 9.8 in older individuals, suggesting that people born before 1950 have residual immunity against the influenza A H1N1 subtype (both seasonal and pandemic).
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subjects Adolescent
Adult
Age Distribution
Age Factors
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Humans
Immunity, Innate - immunology
Incidence
Infant
Infant, Newborn
Influenza A Virus, H1N1 Subtype
Influenza, Human - epidemiology
Influenza, Human - immunology
Male
Middle Aged
Seasons
Spain - epidemiology
Young Adult
title Residual immunity in older people against the influenza A(H1N1)--recent experience in northern Spain
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