$Platelet Microparticles: A Potential Predictive Factor of Survival in Hormone-Refractory Prostate Cancer Patients Treated with Docetaxel-Based Chemotherapy$

Platelet Microparticles: A Potential Predictive Factor of Survival in Hormone-Refractory Prostate Cancer Patients Treated with Docetaxel-Based Chemotherapy

Abstract Background Several studies suggest a causal relationship between platelet activation and cancer metastasis. Activated platelet microparticles (PMPs) release vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), which play a major role in angiogenesis. Objectiv...

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Veröffentlicht in:	European urology 2009-09, Vol.56 (3), p.479-485
Hauptverfasser:	Helley, Dominique, Banu, Eugeniu, Bouziane, Abdelkader, Banu, Adela, Scotte, Florian, Fischer, Anne-Marie, Oudard, Stéphane
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - blood Adenocarcinoma - drug therapy Adenocarcinoma - mortality Adenocarcinoma - surgery Aged Aged, 80 and over Androgen Antagonists - therapeutic use Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Blood Platelets - drug effects Cell-Derived Microparticles - drug effects Humans Male Middle Aged Orchiectomy Prognosis Prospective Studies Prostatic Neoplasms - blood Prostatic Neoplasms - drug therapy Prostatic Neoplasms - mortality Prostatic Neoplasms - surgery Survival Rate Taxoids - pharmacology Taxoids - therapeutic use Treatment Failure Urology
Online-Zugang:	Volltext
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