Raloxifene: its ossification-promoting effect on female mesenchymal stem cells

Raloxifene acts like estrogen in preventing bone loss in postmenopausal women, but it selectively activates biological responses in bone tissue. It has a direct effect on osteoblasts’ differentiation and bone formation in bone marrow culture. However, the point at which raloxifene has an effect on b...

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Veröffentlicht in:	Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2009-09, Vol.14 (5), p.640-645
Hauptverfasser:	Matsumori, Hiroaki, Hattori, Koji, Ohgushi, Hajime, Dohi, Yoshiko, Ueda, Yurito, Shigematsu, Hideki, Satoh, Nobuhisa, Yajima, Hiroshi, Takakura, Yoshinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells Calcification, Physiologic - drug effects Cell Differentiation - drug effects Cells, Cultured Female Male Medicine Medicine & Public Health Mesenchymal Stromal Cells - drug effects Original Article Orthopedics Raloxifene Hydrochloride - pharmacology Rats Rheumatology Selective Estrogen Receptor Modulators - pharmacology Sex Factors
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