Pronounced interferon-alpha production from plasmacytoid dendritic cells in patients with Behçet's disease following CpG D ODN stimulation

Several lines of evidence point to a polarized T-helper-1 (Th1) immune response in Behçet's disease (BD). Interferon (IFN)-alpha which has an ability to promote strong Th1 type immune response has been shown to increase in patients with BD. In order to clarify if plasmacytoid dendritic cells (p...

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Veröffentlicht in:	Clinical and experimental rheumatology 2009-03, Vol.27 (2), p.S37-S42
Hauptverfasser:	PAY, S, PEKEL, A, SIMSEK, I, MUSABAK, U, ERDEM, H, DINC, A, KOSE, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Behcet Syndrome - metabolism Biological and medical sciences Case-Control Studies Cells, Cultured Dendritic Cells - metabolism Diseases of the osteoarticular system Humans Interferon-alpha - metabolism Interferon-beta - metabolism Leukocytes, Mononuclear - metabolism Medical sciences Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Spondylitis, Ankylosing - metabolism
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