discs large regulates somatic cyst cell survival and expansion in Drosophila testis

Gonad development requires a coordinated soma-germline interaction that ensures renewal and differentiation of germline and somatic stem cells to ultimately produce mature gametes. The Drosophila tumour suppressor gene discs large ( dlg ) encodes a septate junction protein functioning during epithel...

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Veröffentlicht in:	Cell research 2009-10, Vol.19 (10), p.1139-1149
Hauptverfasser:	Papagiannouli, Fani, Mechler, Bernard M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Cell Biology Cell Differentiation Cell Proliferation Cell Survival Drosophila - cytology Drosophila - growth & development Drosophila Proteins - genetics Drosophila Proteins - physiology Germ Cells - cytology Life Sciences Male Mutation original-article RNA Interference Spermatocytes - cytology Spermatogenesis - physiology Stem cells Survival Testis - cytology Testis - growth & development Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - physiology
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