Hemodynamic and Renal Effects of the Protein Kinase Inhibitor Staurosporine in Conscious Rats

To evaluate the pattern of hemodynamic responses produced by an inhibitor of protein kinase C (PKC), staurosporine 0.03–0.55 mg/kg was administered intravenously (i.v.) to conscious, normotensive rats chronically instrumented with vascular catheters for direct measurement of blood pressure (BP) and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cardiovascular pharmacology 1992-10, Vol.20 (4), p.525-532
Hauptverfasser:	Dundore, Ronald L, Brousseau, Armand C, Habeeb, Peter G, Pratt, Phillip F, Becker, Lynn T, Clas, Dawn M, Silver, Paul J, Buchholz, R Allan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Antihypertensive agents Biological and medical sciences Cardiac Output - drug effects Cardiovascular system Hemodynamics - drug effects Kidney - drug effects Male Medical sciences Nitrendipine - pharmacology Pharmacology. Drug treatments Protein Kinase C - antagonists & inhibitors Rats Rats, Sprague-Dawley Regional Blood Flow - drug effects Staurosporine Vascular Resistance - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!