Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin

Abstract We present an elastic, fibrous human protein-based and cell-interactive dermal substitute scaffold based on synthetic human elastin. Recombinant human tropoelastin promoted primary human dermal fibroblast attachment, spreading and proliferation. Tropoelastin was cross-linked to form a synth...

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Veröffentlicht in:Biomaterials 2009-11, Vol.30 (32), p.6469-6477
Hauptverfasser: Rnjak, Jelena, Li, Zhe, Maitz, Peter K.M, Wise, Steven G, Weiss, Anthony S
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Sprache:eng
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