DNA analysis from stool samples: a fast and reliable method avoiding invasive sampling methods in mouse models of bleeding disorders

Mouse models with targeted disruptions of coagulation factor genes are used to study disorders of haemostasis such as haemophilia. Standard protocols to obtain biopsies for genotyping in breeding programmes are based on invasive sampling methods such as tail clipping. These procedures imply a high r...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Laboratory animals (London) 2009-10, Vol.43 (4), p.390-393
Hauptverfasser:	Kalippke, Katy, Werwitzke, Sonja, von Hornung, Marcus, Mischke, Reinhard, Ganser, Arnold, Tiede, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal DNA - genetics DNA - isolation & purification Factor VIII - genetics Feces - chemistry Female Genotype Hemophilia A - diagnosis Hemophilia A - genetics Male Mice Mice, Knockout Polymerase Chain Reaction - methods Receptors, IgG - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!