Haplotype-based case–control study between human apurinic/apyrimidinic endonuclease 1/redox effector factor-1 gene and cerebral infarction

The aim of this study was to investigate the relationship between cerebral infarction (CI) and the human apurinic/apyrimidinic endonuclease 1/redox effector factor-1 (APE1/REF-1) gene using single-nucleotide polymorphisms (SNPs) and a haplotype-based case–control study. We selected 5 SNPs in the hum...

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Veröffentlicht in:	Clinical biochemistry 2009-10, Vol.42 (15), p.1493-1499
Hauptverfasser:	Naganuma, Takahiro, Nakayama, Tomohiro, Sato, Naoyuki, Fu, Zhenyan, Yamaguchi, Mai, Soma, Masayoshi, Aoi, Noriko, Usami, Ron, Doba, Nobutaka, Hinohara, Shigeaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Apurinic/apyrimidinic endonuclease 1/redox effector factor-1 Asian Continental Ancestry Group - genetics Case-Control Studies Case–control study Cerebral infarction DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism Female Genes, ras Genetic Markers Genetic Predisposition to Disease Genotype Haplotype Haplotypes Humans Male Middle Aged Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Polymorphism, Single Nucleotide Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism Signal Transduction - physiology Single-nucleotide polymorphism Stroke - genetics
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