Vaginal clear cell adenocarcinoma with associated Müllerian duct anomalies, renal agenesis and situs inversus: Report of a case with no known in-utero exposure with Diethyl stilboestrol
A 27 year old female presented with two months history of continuous vaginal bleeding. On evaluation, she was diagnosed as a case of vaginal clear cell adenocarcinoma (VCCA) along with associated Müllerian duct anomalies including didelphys uterus with double vagina; left sided renal agenesis and si...
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| Veröffentlicht in: | Journal of the Pakistan Medical Association 2009-08, Vol.59 (8), p.568-570 |
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| container_title | Journal of the Pakistan Medical Association |
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| creator | ZEESHAN-UD-DIN AHSAN, Aamir |
| description | A 27 year old female presented with two months history of continuous vaginal bleeding. On evaluation, she was diagnosed as a case of vaginal clear cell adenocarcinoma (VCCA) along with associated Müllerian duct anomalies including didelphys uterus with double vagina; left sided renal agenesis and situs inversus. Although VCCA is strongly linked to in-utero exposure with Diethyl stillboestrol (DES), this patient had no known history regarding such exposure. Also, only a few cases have been described in the literature in which this tumour was seen in association with Müllerian duct anomalies and renal agenesis; in the absence of known DES exposure. |
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On evaluation, she was diagnosed as a case of vaginal clear cell adenocarcinoma (VCCA) along with associated Müllerian duct anomalies including didelphys uterus with double vagina; left sided renal agenesis and situs inversus. Although VCCA is strongly linked to in-utero exposure with Diethyl stillboestrol (DES), this patient had no known history regarding such exposure. Also, only a few cases have been described in the literature in which this tumour was seen in association with Müllerian duct anomalies and renal agenesis; in the absence of known DES exposure.</description><identifier>ISSN: 0030-9982</identifier><identifier>PMID: 19757709</identifier><identifier>CODEN: JJPAD4</identifier><language>eng</language><publisher>Karachi: Pakistan Medical Association</publisher><subject>Adenocarcinoma, Clear Cell - diagnosis ; Adenocarcinoma, Clear Cell - pathology ; Adenocarcinoma, Clear Cell - surgery ; Adult ; Biological and medical sciences ; Carcinogens - toxicity ; Diethylstilbestrol - toxicity ; Female ; General aspects ; Humans ; Kidney - abnormalities ; Kidneys ; Malformations of the urinary system ; Medical sciences ; Mullerian Ducts - pathology ; Nephrology. Urinary tract diseases ; Pregnancy ; Prenatal Exposure Delayed Effects ; Situs Inversus - diagnosis ; Situs Inversus - pathology ; Situs Inversus - surgery ; Uterus - abnormalities ; Vagina - abnormalities ; Vaginal Neoplasms - diagnosis ; Vaginal Neoplasms - pathology ; Vaginal Neoplasms - surgery</subject><ispartof>Journal of the Pakistan Medical Association, 2009-08, Vol.59 (8), p.568-570</ispartof><rights>2015 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22264658$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19757709$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ZEESHAN-UD-DIN</creatorcontrib><creatorcontrib>AHSAN, Aamir</creatorcontrib><title>Vaginal clear cell adenocarcinoma with associated Müllerian duct anomalies, renal agenesis and situs inversus: Report of a case with no known in-utero exposure with Diethyl stilboestrol</title><title>Journal of the Pakistan Medical Association</title><addtitle>J Pak Med Assoc</addtitle><description>A 27 year old female presented with two months history of continuous vaginal bleeding. On evaluation, she was diagnosed as a case of vaginal clear cell adenocarcinoma (VCCA) along with associated Müllerian duct anomalies including didelphys uterus with double vagina; left sided renal agenesis and situs inversus. Although VCCA is strongly linked to in-utero exposure with Diethyl stillboestrol (DES), this patient had no known history regarding such exposure. Also, only a few cases have been described in the literature in which this tumour was seen in association with Müllerian duct anomalies and renal agenesis; in the absence of known DES exposure.</description><subject>Adenocarcinoma, Clear Cell - diagnosis</subject><subject>Adenocarcinoma, Clear Cell - pathology</subject><subject>Adenocarcinoma, Clear Cell - surgery</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Carcinogens - toxicity</subject><subject>Diethylstilbestrol - toxicity</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Kidney - abnormalities</subject><subject>Kidneys</subject><subject>Malformations of the urinary system</subject><subject>Medical sciences</subject><subject>Mullerian Ducts - pathology</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Pregnancy</subject><subject>Prenatal Exposure Delayed Effects</subject><subject>Situs Inversus - diagnosis</subject><subject>Situs Inversus - pathology</subject><subject>Situs Inversus - surgery</subject><subject>Uterus - abnormalities</subject><subject>Vagina - abnormalities</subject><subject>Vaginal Neoplasms - diagnosis</subject><subject>Vaginal Neoplasms - pathology</subject><subject>Vaginal Neoplasms - surgery</subject><issn>0030-9982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo90MFO3DAQBuAcqGC78ApoLhWXRnKSdRxzq2ihSCCkiva6mjiTXYPXDh6nC6-GeuPFmhXbnubwf_pH-g-ymRCVyLVuyqPsI_ODEGUthTjMjgqtpFJCz7LXX7iyHh0YRxjBkHOAHflgMBrrwwZha9MakDkYi4k6uH374xxFix660STAnXKW-DNE2lXhijyx5SnpgG0aGaz_TZFHPocfNISYIPSAYJDpvd4HePRh6yeYj4liAHoeAo9xn3-1lNYvDjhZ1wbiFIM7zj706JhO9nee_bz8dn_xPb-5u7q--HKTD4WUKUfdSoWmr5UpSdWka-qLighlQ6hML5VZNKbFnrTUlegKobpKq6ZoGmpNKat5dvbeO8TwNE6_lxvLu6HQUxh5qaqFWGil9SRP93JsN9Qth2g3GF-W_-aewKc9QDbo-ojeWP7vyrKsF7Vsqr910Y5D</recordid><startdate>200908</startdate><enddate>200908</enddate><creator>ZEESHAN-UD-DIN</creator><creator>AHSAN, Aamir</creator><general>Pakistan Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200908</creationdate><title>Vaginal clear cell adenocarcinoma with associated Müllerian duct anomalies, renal agenesis and situs inversus: Report of a case with no known in-utero exposure with Diethyl stilboestrol</title><author>ZEESHAN-UD-DIN ; AHSAN, Aamir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p155t-a9b57acf67c2e76e96ef13eea58ea7cf57c48cbafe95930d107d3978188ebc253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adenocarcinoma, Clear Cell - diagnosis</topic><topic>Adenocarcinoma, Clear Cell - pathology</topic><topic>Adenocarcinoma, Clear Cell - surgery</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Carcinogens - toxicity</topic><topic>Diethylstilbestrol - toxicity</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Kidney - abnormalities</topic><topic>Kidneys</topic><topic>Malformations of the urinary system</topic><topic>Medical sciences</topic><topic>Mullerian Ducts - pathology</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Pregnancy</topic><topic>Prenatal Exposure Delayed Effects</topic><topic>Situs Inversus - diagnosis</topic><topic>Situs Inversus - pathology</topic><topic>Situs Inversus - surgery</topic><topic>Uterus - abnormalities</topic><topic>Vagina - abnormalities</topic><topic>Vaginal Neoplasms - diagnosis</topic><topic>Vaginal Neoplasms - pathology</topic><topic>Vaginal Neoplasms - surgery</topic><toplevel>online_resources</toplevel><creatorcontrib>ZEESHAN-UD-DIN</creatorcontrib><creatorcontrib>AHSAN, Aamir</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ZEESHAN-UD-DIN</au><au>AHSAN, Aamir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vaginal clear cell adenocarcinoma with associated Müllerian duct anomalies, renal agenesis and situs inversus: Report of a case with no known in-utero exposure with Diethyl stilboestrol</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>2009-08</date><risdate>2009</risdate><volume>59</volume><issue>8</issue><spage>568</spage><epage>570</epage><pages>568-570</pages><issn>0030-9982</issn><coden>JJPAD4</coden><abstract>A 27 year old female presented with two months history of continuous vaginal bleeding. On evaluation, she was diagnosed as a case of vaginal clear cell adenocarcinoma (VCCA) along with associated Müllerian duct anomalies including didelphys uterus with double vagina; left sided renal agenesis and situs inversus. Although VCCA is strongly linked to in-utero exposure with Diethyl stillboestrol (DES), this patient had no known history regarding such exposure. Also, only a few cases have been described in the literature in which this tumour was seen in association with Müllerian duct anomalies and renal agenesis; in the absence of known DES exposure.</abstract><cop>Karachi</cop><pub>Pakistan Medical Association</pub><pmid>19757709</pmid><tpages>3</tpages></addata></record> |
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| ispartof | Journal of the Pakistan Medical Association, 2009-08, Vol.59 (8), p.568-570 |
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| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Adenocarcinoma, Clear Cell - diagnosis Adenocarcinoma, Clear Cell - pathology Adenocarcinoma, Clear Cell - surgery Adult Biological and medical sciences Carcinogens - toxicity Diethylstilbestrol - toxicity Female General aspects Humans Kidney - abnormalities Kidneys Malformations of the urinary system Medical sciences Mullerian Ducts - pathology Nephrology. Urinary tract diseases Pregnancy Prenatal Exposure Delayed Effects Situs Inversus - diagnosis Situs Inversus - pathology Situs Inversus - surgery Uterus - abnormalities Vagina - abnormalities Vaginal Neoplasms - diagnosis Vaginal Neoplasms - pathology Vaginal Neoplasms - surgery |
| title | Vaginal clear cell adenocarcinoma with associated Müllerian duct anomalies, renal agenesis and situs inversus: Report of a case with no known in-utero exposure with Diethyl stilboestrol |
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