Ex vivo generation of mature equine monocyte-derived dendritic cells

Dendritic cells (DCs) are innate immune cells specialized in antigen detection and presentation. They perform an essential role in initiating and guiding the immune response, the direction of which largely depends upon the activation state of the DCs. The objective of this study was to generate matu...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2009-10, Vol.131 (3), p.259-267
Hauptverfasser:	Cavatorta, Derek J., Erb, Hollis N., Flaminio, M. Julia B.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation Antigens, Surface - genetics Antigens, Surface - metabolism Base Sequence biological development Cell Differentiation cell lines Cells, Cultured cytokines Cytokines - genetics Cytokines - metabolism Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology DNA Primers - genetics Endocytosis Equine Escherichia coli Escherichia coli - immunology Gene Expression horses Horses - immunology immune response Immunity, Innate in vitro culture in vitro studies In Vitro Techniques Macrophages Macrophages - cytology Macrophages - immunology major histocompatibility complex Maturation methodology monocytes Monocytes - cytology Monocytes - immunology Receptors, Chemokine - genetics Receptors, Chemokine - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism ultraviolet radiation validity viability
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