Characterization of the human pleiotrophin gene. Promoter region and chromosomal localization

The protein (PTN) encoded by the pleiotrophin (PTN) gene belongs to a recently described family of heparin-binding cytokines whose expression is temporally and spatially regulated during development. We have now isolated genomic clones of the human PTN gene, characterized its promoter region, determ...

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Veröffentlicht in:	The Journal of biological chemistry 1992-12, Vol.267 (36), p.26011-26016
Hauptverfasser:	Y S Li, R M Hoffman, M M Le Beau, R Espinosa, 3rd, N A Jenkins, D J Gilbert, N G Copeland, T F Deuel
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells 5'-terminus Animals Base Sequence binding Biological and medical sciences Carrier Proteins cDNA Chloramphenicol O-Acetyltransferase - genetics Chloramphenicol O-Acetyltransferase - metabolism chromosome 7 Chromosome Banding Chromosome Mapping Chromosomes, Human, Pair 7 Cloning, Molecular Cytokines - genetics DNA Probes Fundamental and applied biological sciences. Psychology genes Genes. Genome Humans localization man Mice Mitogens - genetics Molecular and cellular biology Molecular genetics Molecular Sequence Data MyoD protein nucleotide sequence pleiotrophin Promoter Regions, Genetic promoters Restriction Mapping sites Species Specificity TATA Box Transfection
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