Status of minimal residual disease after induction predicts outcome in both standard and high‐risk Ph‐negative adult acute lymphoblastic leukaemia. The Polish Adult Leukemia Group ALL 4‐2002 MRD Study

Summary The treatment of adults with Philadelphia‐negative acute lymphoblastic leukaemia (ALL) depends on the presence of risk factors including age, white blood cell count, immunophenotype and time to complete remission. In recent years, status of minimal residual disease (MRD) has been postulated...

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Veröffentlicht in:	British journal of haematology 2008-07, Vol.142 (2), p.227-237
Hauptverfasser:	Holowiecki, Jerzy, Krawczyk‐Kulis, Malgorzata, Giebel, Sebastian, Jagoda, Krystyna, Stella‐Holowiecka, Beata, Piatkowska‐Jakubas, Beata, Paluszewska, Monika, Seferynska, Ilona, Lewandowski, Krzysztof, Kielbinski, Marek, Czyz, Anna, Balana‐Nowak, Agnieszka, Król, Maria, Skotnicki, Aleksander B., Jedrzejczak, Wieslaw W., Warzocha, Krzysztof, Lange, Andrzej, Hellmann, Andrzej
Format:	Artikel
Sprache:	eng
Schlagworte:	acute lymphoblastic leukaemia Adolescent Adult Antigens, CD - analysis Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bone Marrow Cells - immunology Female flow cytometry Flow Cytometry - methods Hematologic and hematopoietic diseases Humans Immunophenotyping - methods Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged minimal residual disease Neoplasm, Residual - diagnosis Neoplasm, Residual - immunology Poland Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Predictive Value of Tests Prognosis Prospective Studies Recurrence Risk Young Adult
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