Dendrimers in solution can have their remote catalytic groups folded back into the core: Enantioselective transaminations by dendritic enzyme mimics-II

PAMAM dendrimers, which have double thioether arms, have been synthesized with a pyridoxamine core and chirally terminal amino groups. Transamination to afford natural isomers of phenylalanine and alanine induced enantioselectivity by the peripheral chiral caps, supporting a computer model that indi...

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