Importance of Using Complementary Process Analyzers for the Process Monitoring, Analysis, and Understanding of Freeze Drying

The aim of the present paper is to demonstrate the importance of using complementary process analyzers (PAT tools) for the process monitoring, analysis, and understanding of freeze drying. A mannitol solution was used as a model system. Raman spectroscopic, near-infrared (NIR) spectroscopic, plasma...

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Veröffentlicht in:	Analytical chemistry (Washington) 2009-09, Vol.81 (18), p.7639-7649
Hauptverfasser:	De Beer, T. R. M, Wiggenhorn, M, Veillon, R, Debacq, C, Mayeresse, Y, Moreau, B, Burggraeve, A, Quinten, T, Friess, W, Winter, G, Vervaet, C, Remon, J. P, Baeyens, W. R. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Data analysis Exact sciences and technology Freeze Drying - instrumentation Freeze Drying - methods Freezing Mannitol - chemistry Principal Component Analysis Spectrometric and optical methods Spectroscopy, Near-Infrared Spectrum analysis Spectrum Analysis, Raman Studies Temperature
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