$Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival$

Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival

Summary Allogeneic stem cell transplantation (alloSCT) for patients with refractory anaemia may result in a 50% event‐free survival, but the high non‐relapse mortality (NRM) precludes a general application of this therapeutic modality. This study evaluated the impact of various pre‐transplant variab...

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Veröffentlicht in:	British journal of haematology 2009-09, Vol.146 (6), p.627-636
Hauptverfasser:	De Witte, Theo, Brand, Ronald, Van Biezen, Anja, Mufti, Ghulam, Ruutu, Tapani, Finke, Jürgen, Von Dem Borne, Peter, Vitek, Antonin, Delforge, Michel, Alessandrino, Paolo, Harlahakis, Nicolas, Russell, Nigel, Martino, Roberto, Verdonck, Leo, Kröger, Nicholas, Niederwieser, Dietger
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult allogeneic stem cell transplantation Anemia, Refractory - mortality Anemia, Refractory - therapy Biological and medical sciences Disease-Free Survival Female Hematologic and hematopoietic diseases Histocompatibility Testing HLA‐identical sibling donor Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male matched unrelated donor Medical sciences Middle Aged Multivariate Analysis reduced intensity conditioning regimens refractory anaemia Risk Factors Siblings Stem Cell Transplantation - methods Stem Cell Transplantation - mortality Time Factors Tissue Donors - statistics & numerical data Transplantation Conditioning - methods Young Adult
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