The second bovine beta-galactoside-alpha2,6-sialyltransferase (ST6Gal II): genomic organization and stimulation of its in vitro expression by IL-6 in bovine mammary epithelial cells

We have cloned a cDNA sequence encoding the second bovine beta-galactoside-alpha2,6-sialyltransferase whose sequence shares more than 75% of identity with hST6Gal II cDNA coding sequence. The bovine gene, located on BTA 11, spans over 50 kbp with five exons (E1-E5) containing the 1488 bp open readin...

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Veröffentlicht in:	Glycobiology (Oxford) 2009-10, Vol.19 (10), p.1082-1093
Hauptverfasser:	Laporte, Benoit, Gonzalez-Hilarion, Sara, Maftah, Abderrahman, Petit, Jean-Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions Amino Acid Sequence Animals Base Sequence Cattle Cells, Cultured Cloning, Molecular DNA, Complementary - genetics Epithelial Cells - metabolism Female Gene Expression - drug effects Genome Humans Interleukin-6 - metabolism Mammary Glands, Animal - metabolism Molecular Sequence Data Organ Specificity Sequence Alignment Sequence Homology, Amino Acid Sialyltransferases - chemistry Sialyltransferases - genetics Sialyltransferases - metabolism Transcription, Genetic
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