ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients

The human activating immune receptor, NKG2D, binds to a diverse array of cellular ligands of the MIC and unique long 16 (UL16)‐binding protein (ULBP)/retinoic acid early transcript (RAET) family. NKG2D is thought to participate in anticancer immune responses. By using tissue microarrays representing...

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Veröffentlicht in:	International journal of cancer 2010-09, Vol.127 (6), p.1412-1420
Hauptverfasser:	McGilvray, Roger W., Eagle, Robert A., Rolland, Phil, Jafferji, Insiya, Trowsdale, John, Durrant, Lindy G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Carrier Proteins - metabolism Female Female genital diseases GPI-Linked Proteins Gynecology. Andrology. Obstetrics Histocompatibility Antigens Class I - metabolism Humans Immunohistochemistry Intercellular Signaling Peptides and Proteins - metabolism Ligands Medical sciences Membrane Proteins - metabolism Middle Aged NKG2D ovarian cancer Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology predictive markers Prognosis Tumors
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