The structure of invadopodia in a complex 3D environment

Invadopodia and podosomes have been intensively studied because of their involvement in the degradation of extracellular matrix. As both structures have been studied mostly on thin matrices, their commonly reported shapes and characteristics may differ from those in vivo. To assess the morphology of...

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Veröffentlicht in:	European journal of cell biology 2010-09, Vol.89 (9), p.674-680
Hauptverfasser:	Tolde, Ondřej, Rösel, Daniel, Veselý, Pavel, Folk, Petr, Brábek, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Cell Culture Techniques Cell Line, Tumor Cell Surface Extensions - metabolism Cell Surface Extensions - ultrastructure Cortactin - metabolism Cytoskeleton - metabolism Extracellular Matrix - metabolism Extracellular Matrix - physiology Extracellular Matrix - ultrastructure Fluorescent Antibody Technique Humans Imaging, Three-Dimensional Invadopodia Invasiveness Microscopy, Electron Podosomes Rats Sarcoma Sarcoma, Experimental - metabolism Sarcoma, Experimental - ultrastructure SEM Signal Transduction Swine TEM
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