Inhibition of tubulin-dependent ATPase activity in microtubule proteins from porcine brain by S100 protein

Microtubule-associated proteins (MAPs) of brain microtubules exhibit an ATPase activity which is markedly enhanced by tubulin and Ca 2+. Addition of S100 protein decreased the tubulindependent Ca 2+-ATPase activity by about 85%, but did not affect the activity without tubulin. The inhibition by S100...

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Veröffentlicht in:Neurochemistry international 1988, Vol.13 (4), p.509-516
Hauptverfasser: Asai, Haruo, Miyasaka, Yukihiro, Kondo, Yoshiyuki, Fuju, Toshihiro
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Sprache:eng
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