6 Iodo-δ-lactone reproduces many but not all the effects of iodide

Iodide has direct effects on thyroid function. Several iodinated lipids are biosynthesized by the thyroid and they were postulated as intermediaries in the action of iodide. Among them 6 iodo-δ-lactone (IL-δ) has been identified and proposed to play a role in thyroid autoregulation. The aim of this...

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Veröffentlicht in:	Molecular and cellular endocrinology 2010-07, Vol.323 (2), p.161-166
Hauptverfasser:	Thomasz, Lisa, Oglio, Romina, Dagrosa, María A., Krawiec, León, Pisarev, Mario A., Juvenal, Guillermo J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acids - metabolism Arachidonic Acids - pharmacology Cattle Cells, Cultured Humans Iodide Iodides - metabolism Iodides - pharmacology Iodine Radioisotopes - metabolism Iodolipids Potassium Iodide - metabolism Potassium Iodide - pharmacology Thyroid cell regulation Thyroid follicles (bovine) Thyroid Gland - drug effects Thyroid Gland - metabolism
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