The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro

Aims A problem in generating artificial tissues is supplying nutrients to cells within 3D constructs. The use of a decellularized biological vascularized matrix with preserved pedicles (BioVaM), as a scaffold, appears to aid the generation of perfusable tissue constructs in vitro. To prevent vessel...

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Veröffentlicht in:	Cardiovascular research 2010-03, Vol.85 (4), p.806-813
Hauptverfasser:	Bär, Antonia, Dorfman, Suzanne E., Fischer, Philipp, Hilfiker-Kleiner, Denise, Cebotari, Serghei, Tudorache, Igor, Suprunov, Marc, Haverich, Axel, Hilfiker, Andres
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiology. Vascular system CCN1 Cell Adhesion - drug effects Cell Culture Techniques - methods Cell Differentiation - drug effects Cell Division - drug effects Cells, Cultured Cysteine-Rich Protein 61 - pharmacology Endothelial Cells - drug effects Endothelium Extracellular matrix Extracellular Matrix - drug effects Fetal Blood - cytology Humans Medical sciences Neovascularization, Physiologic - drug effects Tissue engineering Tissue Engineering - methods
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