Hydroxyisohexyl 3-cyclohexene carboxaldehyde allergy: relationship between patch test and repeated open application test thresholds

Summary Background Hydroxyisohexyl 3‐cyclohexene carboxaldehyde (HICC) is a synthetic fragrance ingredient. Case reports of allergy to HICC appeared in the 1980s, and HICC has recently been included in the European baseline series. Human elicitation dose–response studies performed with different al...

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Veröffentlicht in:	British journal of dermatology (1951) 2009-09, Vol.161 (3), p.560-567
Hauptverfasser:	Fischer, L.A., Menné, T., Avnstorp, C., Kasting, G.B., Johansen, J.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aldehydes - adverse effects Allergens - administration & dosage Allergens - adverse effects Biological and medical sciences Cyclohexanes - adverse effects Cyclohexenes - adverse effects Dermatitis, Allergic Contact - diagnosis Dermatitis, Allergic Contact - etiology Dermatology dose-response Dose-Response Relationship, Drug elicitation Female HICC allergy Humans Logistic Models Male Medical sciences Middle Aged patch test Patch Tests - methods Perfume - adverse effects Perfume - chemistry repeated exposure ROAT Young Adult
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