Endogenous modulation of the blunted adrenergic response in resistance-sized mesenteric arteries from the pregnant rat

OBJECTIVE: We tested the hypothesis that during pregnancy the endothelium mediates the blunted response to adrenergic vasoconstriction. STUDY DESIGN: Mesenteric resistance arteries from late pregnant (n = 6) and age-matched virgin control (n = 6) Sprague-Dawley rats were studied in a myograph. RESUL...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of obstetrics and gynecology 1992-12, Vol.167 (6), p.1691-1698
Hauptverfasser:	Davidge, Sandra T., McLaughlin, Margaret K.
Format:	Artikel
Sprache:	eng
Schlagworte:	adrenergic vascular reactivity Animals Arginine - analogs & derivatives Arginine - pharmacology Biological and medical sciences Dose-Response Relationship, Drug endothelium Endothelium, Vascular - physiology Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Meclofenamic Acid - pharmacology Mesenteric Arteries - physiology Methacholine Chloride - pharmacology NG-Nitroarginine Methyl Ester Nitric Oxide - antagonists & inhibitors Phenylephrine - pharmacology Pilot Projects Pregnancy Pregnancy, Animal - physiology Pregnancy. Parturition. Lactation Rats Rats, Sprague-Dawley resistance arteries Sprague-Dawley rat Sympathetic Nervous System - physiology Vascular Resistance - drug effects Vertebrates: reproduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!