Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series
Purpose To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients. Patients and methods Medical records of 326 consecutive patients undergoing radical cystectomy from May 2004 through April 2008 were re...
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| Veröffentlicht in: | World journal of urology 2010-08, Vol.28 (4), p.445-450 |
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| creator | Tilki, Derya Zaak, Dirk Trottmann, Matthias Buchner, Alexander Ekiz, Yeliz Gerwens, Niklas Schlenker, Boris Karl, Alexander Walther, Sebastian Bastian, Patrick J. Gratzke, Christian Tritschler, Stefan Knüchel-Clarke, Ruth Ergün, Süleyman Stief, Christian G. Reich, Oliver Seitz, Michael |
| description | Purpose
To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients.
Patients and methods
Medical records of 326 consecutive patients undergoing radical cystectomy from May 2004 through April 2008 were reviewed.
Results
Eighty-five of 326 patients (26%) were ≥75 years (75–95) old. ASA score was equal 3 or greater in 51% of patients ≥75 years and 32% of patients |
| doi_str_mv | 10.1007/s00345-009-0482-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_734008676</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>734008676</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-5ed876bfe46ab8e3152edd9350e26a0c985ba9346f16c8e4a5eea761eee7a1af3</originalsourceid><addsrcrecordid>eNp1kU2LFDEQhoMo7rj6A7xIEMRTa6Xz2d5k8QsWBNFzyKSr1yzdSZukhbn6y804gwuClyTF-9RbRV5CnjJ4xQD06wLAhewAhg6E6Tt2j-yY4Lwzulf3yQ50LzoxGH5BHpVyC8C0AvmQXLDBCC34sCO_vrgxeDdTfygVfU3LgYZI63ekOI-Y5wNdXQ0Y6xvqqE-x4rKm7PKhFcvqcigp0jTRFXNI7WjwT_yjzc23hhTL0dDREuLNjO1daqjbUaCl9WB5TB5Mbi745Hxfkm_v3329-thdf_7w6ertdecFQO0kjkar_YRCub1BzmSP4zhwCdgrB34wcu8GLtTElDconER0WjFE1I65iV-SlyffNacfG5Zql1A8zrOLmLZiNW9zjNKqkc__IW_TlmNbrkFaMgGSN4idIJ9TKRknu-awtI-xDOwxHnuKx7Z47DEey1rPs7Pxtl9wvOs459GAF2fAlZbKlF30ofzleg5aSG0a15-40qR4g_luw_9P_w1S3arp</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>737514053</pqid></control><display><type>article</type><title>Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Tilki, Derya ; Zaak, Dirk ; Trottmann, Matthias ; Buchner, Alexander ; Ekiz, Yeliz ; Gerwens, Niklas ; Schlenker, Boris ; Karl, Alexander ; Walther, Sebastian ; Bastian, Patrick J. ; Gratzke, Christian ; Tritschler, Stefan ; Knüchel-Clarke, Ruth ; Ergün, Süleyman ; Stief, Christian G. ; Reich, Oliver ; Seitz, Michael</creator><creatorcontrib>Tilki, Derya ; Zaak, Dirk ; Trottmann, Matthias ; Buchner, Alexander ; Ekiz, Yeliz ; Gerwens, Niklas ; Schlenker, Boris ; Karl, Alexander ; Walther, Sebastian ; Bastian, Patrick J. ; Gratzke, Christian ; Tritschler, Stefan ; Knüchel-Clarke, Ruth ; Ergün, Süleyman ; Stief, Christian G. ; Reich, Oliver ; Seitz, Michael</creatorcontrib><description>Purpose
To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients.
Patients and methods
Medical records of 326 consecutive patients undergoing radical cystectomy from May 2004 through April 2008 were reviewed.
Results
Eighty-five of 326 patients (26%) were ≥75 years (75–95) old. ASA score was equal 3 or greater in 51% of patients ≥75 years and 32% of patients <75 years. Ileal conduit was performed in 83% of patients ≥75, 16% received an ileal neobladder compared to 46 and 51%, respectively, in patients <75. A total of 33 patients (39%) in the older patient group received blood transfusions intraoperatively compared to 76 patients (32%) in the younger age group. In 6 patients ≥75 years (7.1%) and 17 patients <75 (7.1%) open surgical revision was necessary, perioperative complication rate was 22 and 21%, respectively. The most common complications were wound dehiscence (5.9 vs. 7.5%), infections (4.7 vs. 4.6%), and pulmonary embolism (3.5 vs. 2.1%). Perioperative mortality was 1.2% (1 patient) in the elderly versus 0.4% (1 patient) in the younger age group.
Conclusion
Our data show that radical cystectomy can be offered to the elderly patient with acceptable morbidity. Because of higher comorbidity rate in the elderly, therapeutic decision for radical cystectomy in elderly patients should be made carefully and individually. Nevertheless our results demonstrate that age itself is not a main criterion which has to be considered strongly in decision making for radical cystectomy.</description><identifier>ISSN: 0724-4983</identifier><identifier>EISSN: 1433-8726</identifier><identifier>DOI: 10.1007/s00345-009-0482-1</identifier><identifier>PMID: 19847439</identifier><identifier>CODEN: WJURDJ</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject><![CDATA[Adenocarcinoma - epidemiology ; Adenocarcinoma - pathology ; Adenocarcinoma - surgery ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Blood Loss, Surgical - statistics & numerical data ; Blood Transfusion - statistics & numerical data ; Carcinoma, Squamous Cell - epidemiology ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - surgery ; Cystectomy - adverse effects ; Cystectomy - methods ; Cystectomy - statistics & numerical data ; Female ; Humans ; Incidence ; Intraoperative Complications - epidemiology ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Melanoma - epidemiology ; Melanoma - pathology ; Melanoma - surgery ; Morbidity ; Neoplasm Staging - statistics & numerical data ; Nephrology ; Nephrology. Urinary tract diseases ; Neuroendocrine Tumors - epidemiology ; Neuroendocrine Tumors - pathology ; Neuroendocrine Tumors - surgery ; Oncology ; Original Article ; Outcome Assessment (Health Care) ; Reoperation - statistics & numerical data ; Tumors of the urinary system ; Urinary Bladder Neoplasms - epidemiology ; Urinary Bladder Neoplasms - pathology ; Urinary Bladder Neoplasms - surgery ; Urinary system involvement in other diseases. Miscellaneous ; Urinary tract. Prostate gland ; Urology]]></subject><ispartof>World journal of urology, 2010-08, Vol.28 (4), p.445-450</ispartof><rights>Springer-Verlag 2009</rights><rights>2015 INIST-CNRS</rights><rights>Springer-Verlag 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-5ed876bfe46ab8e3152edd9350e26a0c985ba9346f16c8e4a5eea761eee7a1af3</citedby><cites>FETCH-LOGICAL-c400t-5ed876bfe46ab8e3152edd9350e26a0c985ba9346f16c8e4a5eea761eee7a1af3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00345-009-0482-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00345-009-0482-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23074578$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19847439$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tilki, Derya</creatorcontrib><creatorcontrib>Zaak, Dirk</creatorcontrib><creatorcontrib>Trottmann, Matthias</creatorcontrib><creatorcontrib>Buchner, Alexander</creatorcontrib><creatorcontrib>Ekiz, Yeliz</creatorcontrib><creatorcontrib>Gerwens, Niklas</creatorcontrib><creatorcontrib>Schlenker, Boris</creatorcontrib><creatorcontrib>Karl, Alexander</creatorcontrib><creatorcontrib>Walther, Sebastian</creatorcontrib><creatorcontrib>Bastian, Patrick J.</creatorcontrib><creatorcontrib>Gratzke, Christian</creatorcontrib><creatorcontrib>Tritschler, Stefan</creatorcontrib><creatorcontrib>Knüchel-Clarke, Ruth</creatorcontrib><creatorcontrib>Ergün, Süleyman</creatorcontrib><creatorcontrib>Stief, Christian G.</creatorcontrib><creatorcontrib>Reich, Oliver</creatorcontrib><creatorcontrib>Seitz, Michael</creatorcontrib><title>Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series</title><title>World journal of urology</title><addtitle>World J Urol</addtitle><addtitle>World J Urol</addtitle><description>Purpose
To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients.
Patients and methods
Medical records of 326 consecutive patients undergoing radical cystectomy from May 2004 through April 2008 were reviewed.
Results
Eighty-five of 326 patients (26%) were ≥75 years (75–95) old. ASA score was equal 3 or greater in 51% of patients ≥75 years and 32% of patients <75 years. Ileal conduit was performed in 83% of patients ≥75, 16% received an ileal neobladder compared to 46 and 51%, respectively, in patients <75. A total of 33 patients (39%) in the older patient group received blood transfusions intraoperatively compared to 76 patients (32%) in the younger age group. In 6 patients ≥75 years (7.1%) and 17 patients <75 (7.1%) open surgical revision was necessary, perioperative complication rate was 22 and 21%, respectively. The most common complications were wound dehiscence (5.9 vs. 7.5%), infections (4.7 vs. 4.6%), and pulmonary embolism (3.5 vs. 2.1%). Perioperative mortality was 1.2% (1 patient) in the elderly versus 0.4% (1 patient) in the younger age group.
Conclusion
Our data show that radical cystectomy can be offered to the elderly patient with acceptable morbidity. Because of higher comorbidity rate in the elderly, therapeutic decision for radical cystectomy in elderly patients should be made carefully and individually. Nevertheless our results demonstrate that age itself is not a main criterion which has to be considered strongly in decision making for radical cystectomy.</description><subject>Adenocarcinoma - epidemiology</subject><subject>Adenocarcinoma - pathology</subject><subject>Adenocarcinoma - surgery</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Blood Loss, Surgical - statistics & numerical data</subject><subject>Blood Transfusion - statistics & numerical data</subject><subject>Carcinoma, Squamous Cell - epidemiology</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Cystectomy - adverse effects</subject><subject>Cystectomy - methods</subject><subject>Cystectomy - statistics & numerical data</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Intraoperative Complications - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Melanoma - epidemiology</subject><subject>Melanoma - pathology</subject><subject>Melanoma - surgery</subject><subject>Morbidity</subject><subject>Neoplasm Staging - statistics & numerical data</subject><subject>Nephrology</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Neuroendocrine Tumors - epidemiology</subject><subject>Neuroendocrine Tumors - pathology</subject><subject>Neuroendocrine Tumors - surgery</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Outcome Assessment (Health Care)</subject><subject>Reoperation - statistics & numerical data</subject><subject>Tumors of the urinary system</subject><subject>Urinary Bladder Neoplasms - epidemiology</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Urinary Bladder Neoplasms - surgery</subject><subject>Urinary system involvement in other diseases. Miscellaneous</subject><subject>Urinary tract. Prostate gland</subject><subject>Urology</subject><issn>0724-4983</issn><issn>1433-8726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kU2LFDEQhoMo7rj6A7xIEMRTa6Xz2d5k8QsWBNFzyKSr1yzdSZukhbn6y804gwuClyTF-9RbRV5CnjJ4xQD06wLAhewAhg6E6Tt2j-yY4Lwzulf3yQ50LzoxGH5BHpVyC8C0AvmQXLDBCC34sCO_vrgxeDdTfygVfU3LgYZI63ekOI-Y5wNdXQ0Y6xvqqE-x4rKm7PKhFcvqcigp0jTRFXNI7WjwT_yjzc23hhTL0dDREuLNjO1daqjbUaCl9WB5TB5Mbi745Hxfkm_v3329-thdf_7w6ertdecFQO0kjkar_YRCub1BzmSP4zhwCdgrB34wcu8GLtTElDconER0WjFE1I65iV-SlyffNacfG5Zql1A8zrOLmLZiNW9zjNKqkc__IW_TlmNbrkFaMgGSN4idIJ9TKRknu-awtI-xDOwxHnuKx7Z47DEey1rPs7Pxtl9wvOs459GAF2fAlZbKlF30ofzleg5aSG0a15-40qR4g_luw_9P_w1S3arp</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Tilki, Derya</creator><creator>Zaak, Dirk</creator><creator>Trottmann, Matthias</creator><creator>Buchner, Alexander</creator><creator>Ekiz, Yeliz</creator><creator>Gerwens, Niklas</creator><creator>Schlenker, Boris</creator><creator>Karl, Alexander</creator><creator>Walther, Sebastian</creator><creator>Bastian, Patrick J.</creator><creator>Gratzke, Christian</creator><creator>Tritschler, Stefan</creator><creator>Knüchel-Clarke, Ruth</creator><creator>Ergün, Süleyman</creator><creator>Stief, Christian G.</creator><creator>Reich, Oliver</creator><creator>Seitz, Michael</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20100801</creationdate><title>Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series</title><author>Tilki, Derya ; Zaak, Dirk ; Trottmann, Matthias ; Buchner, Alexander ; Ekiz, Yeliz ; Gerwens, Niklas ; Schlenker, Boris ; Karl, Alexander ; Walther, Sebastian ; Bastian, Patrick J. ; Gratzke, Christian ; Tritschler, Stefan ; Knüchel-Clarke, Ruth ; Ergün, Süleyman ; Stief, Christian G. ; Reich, Oliver ; Seitz, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-5ed876bfe46ab8e3152edd9350e26a0c985ba9346f16c8e4a5eea761eee7a1af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adenocarcinoma - epidemiology</topic><topic>Adenocarcinoma - pathology</topic><topic>Adenocarcinoma - surgery</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Blood Loss, Surgical - statistics & numerical data</topic><topic>Blood Transfusion - statistics & numerical data</topic><topic>Carcinoma, Squamous Cell - epidemiology</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Cystectomy - adverse effects</topic><topic>Cystectomy - methods</topic><topic>Cystectomy - statistics & numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Intraoperative Complications - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Melanoma - epidemiology</topic><topic>Melanoma - pathology</topic><topic>Melanoma - surgery</topic><topic>Morbidity</topic><topic>Neoplasm Staging - statistics & numerical data</topic><topic>Nephrology</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Neuroendocrine Tumors - epidemiology</topic><topic>Neuroendocrine Tumors - pathology</topic><topic>Neuroendocrine Tumors - surgery</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Outcome Assessment (Health Care)</topic><topic>Reoperation - statistics & numerical data</topic><topic>Tumors of the urinary system</topic><topic>Urinary Bladder Neoplasms - epidemiology</topic><topic>Urinary Bladder Neoplasms - pathology</topic><topic>Urinary Bladder Neoplasms - surgery</topic><topic>Urinary system involvement in other diseases. Miscellaneous</topic><topic>Urinary tract. Prostate gland</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tilki, Derya</creatorcontrib><creatorcontrib>Zaak, Dirk</creatorcontrib><creatorcontrib>Trottmann, Matthias</creatorcontrib><creatorcontrib>Buchner, Alexander</creatorcontrib><creatorcontrib>Ekiz, Yeliz</creatorcontrib><creatorcontrib>Gerwens, Niklas</creatorcontrib><creatorcontrib>Schlenker, Boris</creatorcontrib><creatorcontrib>Karl, Alexander</creatorcontrib><creatorcontrib>Walther, Sebastian</creatorcontrib><creatorcontrib>Bastian, Patrick J.</creatorcontrib><creatorcontrib>Gratzke, Christian</creatorcontrib><creatorcontrib>Tritschler, Stefan</creatorcontrib><creatorcontrib>Knüchel-Clarke, Ruth</creatorcontrib><creatorcontrib>Ergün, Süleyman</creatorcontrib><creatorcontrib>Stief, Christian G.</creatorcontrib><creatorcontrib>Reich, Oliver</creatorcontrib><creatorcontrib>Seitz, Michael</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tilki, Derya</au><au>Zaak, Dirk</au><au>Trottmann, Matthias</au><au>Buchner, Alexander</au><au>Ekiz, Yeliz</au><au>Gerwens, Niklas</au><au>Schlenker, Boris</au><au>Karl, Alexander</au><au>Walther, Sebastian</au><au>Bastian, Patrick J.</au><au>Gratzke, Christian</au><au>Tritschler, Stefan</au><au>Knüchel-Clarke, Ruth</au><au>Ergün, Süleyman</au><au>Stief, Christian G.</au><au>Reich, Oliver</au><au>Seitz, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series</atitle><jtitle>World journal of urology</jtitle><stitle>World J Urol</stitle><addtitle>World J Urol</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>28</volume><issue>4</issue><spage>445</spage><epage>450</epage><pages>445-450</pages><issn>0724-4983</issn><eissn>1433-8726</eissn><coden>WJURDJ</coden><abstract>Purpose
To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients.
Patients and methods
Medical records of 326 consecutive patients undergoing radical cystectomy from May 2004 through April 2008 were reviewed.
Results
Eighty-five of 326 patients (26%) were ≥75 years (75–95) old. ASA score was equal 3 or greater in 51% of patients ≥75 years and 32% of patients <75 years. Ileal conduit was performed in 83% of patients ≥75, 16% received an ileal neobladder compared to 46 and 51%, respectively, in patients <75. A total of 33 patients (39%) in the older patient group received blood transfusions intraoperatively compared to 76 patients (32%) in the younger age group. In 6 patients ≥75 years (7.1%) and 17 patients <75 (7.1%) open surgical revision was necessary, perioperative complication rate was 22 and 21%, respectively. The most common complications were wound dehiscence (5.9 vs. 7.5%), infections (4.7 vs. 4.6%), and pulmonary embolism (3.5 vs. 2.1%). Perioperative mortality was 1.2% (1 patient) in the elderly versus 0.4% (1 patient) in the younger age group.
Conclusion
Our data show that radical cystectomy can be offered to the elderly patient with acceptable morbidity. Because of higher comorbidity rate in the elderly, therapeutic decision for radical cystectomy in elderly patients should be made carefully and individually. Nevertheless our results demonstrate that age itself is not a main criterion which has to be considered strongly in decision making for radical cystectomy.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>19847439</pmid><doi>10.1007/s00345-009-0482-1</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | World journal of urology, 2010-08, Vol.28 (4), p.445-450 |
| issn | 0724-4983 1433-8726 |
| language | eng |
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| subjects | Adenocarcinoma - epidemiology Adenocarcinoma - pathology Adenocarcinoma - surgery Aged Aged, 80 and over Biological and medical sciences Blood Loss, Surgical - statistics & numerical data Blood Transfusion - statistics & numerical data Carcinoma, Squamous Cell - epidemiology Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Cystectomy - adverse effects Cystectomy - methods Cystectomy - statistics & numerical data Female Humans Incidence Intraoperative Complications - epidemiology Male Medical sciences Medicine Medicine & Public Health Melanoma - epidemiology Melanoma - pathology Melanoma - surgery Morbidity Neoplasm Staging - statistics & numerical data Nephrology Nephrology. Urinary tract diseases Neuroendocrine Tumors - epidemiology Neuroendocrine Tumors - pathology Neuroendocrine Tumors - surgery Oncology Original Article Outcome Assessment (Health Care) Reoperation - statistics & numerical data Tumors of the urinary system Urinary Bladder Neoplasms - epidemiology Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - surgery Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland Urology |
| title | Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series |
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