A Systematic Review of the Factors Affecting Accuracy of SUV Measurements
There is growing interest in using PET/CT for evaluating early response to therapy in cancer treatment. Although widely available and convenient to use, standardized uptake value (SUV) measurements can be influenced by a variety of biologic and technologic factors. Many of these factors can be addre...
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Veröffentlicht in: | American journal of roentgenology (1976) 2010-08, Vol.195 (2), p.310-320 |
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container_title | American journal of roentgenology (1976) |
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creator | ADAMS, Michael C TURKINGTON, Timothy G WILSON, Joshua M WONG, Terence Z |
description | There is growing interest in using PET/CT for evaluating early response to therapy in cancer treatment. Although widely available and convenient to use, standardized uptake value (SUV) measurements can be influenced by a variety of biologic and technologic factors. Many of these factors can be addressed with close attention to detail and appropriate quality control. This article will review factors potentially affecting SUV measurements and provide recommendations on ways to minimize when using serial PET to assess early response to therapy.
Scanner and reconstruction parameters can significantly affect SUV measurements. When using serial SUV measurements to assess early response to therapy, imaging should be performed on the same scanner using the same image acquisition and reconstruction protocols. In addition, attention to detail is required for accurate determination of the administered radiopharmaceutical dose. |
doi_str_mv | 10.2214/ajr.10.4923 |
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Scanner and reconstruction parameters can significantly affect SUV measurements. When using serial SUV measurements to assess early response to therapy, imaging should be performed on the same scanner using the same image acquisition and reconstruction protocols. In addition, attention to detail is required for accurate determination of the administered radiopharmaceutical dose.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/ajr.10.4923</identifier><identifier>PMID: 20651185</identifier><identifier>CODEN: AAJRDX</identifier><language>eng</language><publisher>Reston, VA: American Roentgen Ray Society</publisher><subject>Algorithms ; Biological and medical sciences ; Fluorodeoxyglucose F18 - pharmacokinetics ; Humans ; Image Enhancement - methods ; Image Interpretation, Computer-Assisted - methods ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Models, Biological ; Neoplasms - diagnostic imaging ; Neoplasms - metabolism ; Positron-Emission Tomography - methods ; Radiopharmaceuticals - pharmacokinetics ; Reproducibility of Results ; Sensitivity and Specificity</subject><ispartof>American journal of roentgenology (1976), 2010-08, Vol.195 (2), p.310-320</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-537317a78182d1ce69ecd17917469f671704aafcf8604d3e44606d1e94e5550f3</citedby><cites>FETCH-LOGICAL-c426t-537317a78182d1ce69ecd17917469f671704aafcf8604d3e44606d1e94e5550f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4106,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23050775$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20651185$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ADAMS, Michael C</creatorcontrib><creatorcontrib>TURKINGTON, Timothy G</creatorcontrib><creatorcontrib>WILSON, Joshua M</creatorcontrib><creatorcontrib>WONG, Terence Z</creatorcontrib><title>A Systematic Review of the Factors Affecting Accuracy of SUV Measurements</title><title>American journal of roentgenology (1976)</title><addtitle>AJR Am J Roentgenol</addtitle><description>There is growing interest in using PET/CT for evaluating early response to therapy in cancer treatment. Although widely available and convenient to use, standardized uptake value (SUV) measurements can be influenced by a variety of biologic and technologic factors. Many of these factors can be addressed with close attention to detail and appropriate quality control. This article will review factors potentially affecting SUV measurements and provide recommendations on ways to minimize when using serial PET to assess early response to therapy.
Scanner and reconstruction parameters can significantly affect SUV measurements. When using serial SUV measurements to assess early response to therapy, imaging should be performed on the same scanner using the same image acquisition and reconstruction protocols. In addition, attention to detail is required for accurate determination of the administered radiopharmaceutical dose.</description><subject>Algorithms</subject><subject>Biological and medical sciences</subject><subject>Fluorodeoxyglucose F18 - pharmacokinetics</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Models, Biological</subject><subject>Neoplasms - diagnostic imaging</subject><subject>Neoplasms - metabolism</subject><subject>Positron-Emission Tomography - methods</subject><subject>Radiopharmaceuticals - pharmacokinetics</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0D1PwzAYBGALgWgpTOwoC2JAKXb8lYxRRaGoCKmliC0yzmtIlY9iO6D-exK1wHQ3PLrhEDoneBxFhN2otR13nSURPUBDwpkIKWHkEA0xFSSMMX0doBPn1hhjGSfyGA0iLDghMR-iWRost85DpXyhgwV8FfAdNCbwHxBMlfaNdUFqDGhf1O9BqnVrld72Yrl6CR5BudZCBbV3p-jIqNLB2T5HaDW9fZ7ch_Onu9kknYeaRcKHnEpKpJIxiaOcaBAJ6JzIhEgmEiMkkZgpZbSJBWY5BcYEFjmBhAHnHBs6Qle73Y1tPltwPqsKp6EsVQ1N6zJJGcY8iuJOXu-kto1zFky2sUWl7DYjOOuvy9KHRd_76zp9sd9t3yrI_-zvVx243APltCqNVbUu3L-jmGMpOf0BbmR0Mw</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>ADAMS, Michael C</creator><creator>TURKINGTON, Timothy G</creator><creator>WILSON, Joshua M</creator><creator>WONG, Terence Z</creator><general>American Roentgen Ray Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100801</creationdate><title>A Systematic Review of the Factors Affecting Accuracy of SUV Measurements</title><author>ADAMS, Michael C ; TURKINGTON, Timothy G ; WILSON, Joshua M ; WONG, Terence Z</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-537317a78182d1ce69ecd17917469f671704aafcf8604d3e44606d1e94e5550f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Algorithms</topic><topic>Biological and medical sciences</topic><topic>Fluorodeoxyglucose F18 - pharmacokinetics</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Models, Biological</topic><topic>Neoplasms - diagnostic imaging</topic><topic>Neoplasms - metabolism</topic><topic>Positron-Emission Tomography - methods</topic><topic>Radiopharmaceuticals - pharmacokinetics</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ADAMS, Michael C</creatorcontrib><creatorcontrib>TURKINGTON, Timothy G</creatorcontrib><creatorcontrib>WILSON, Joshua M</creatorcontrib><creatorcontrib>WONG, Terence Z</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ADAMS, Michael C</au><au>TURKINGTON, Timothy G</au><au>WILSON, Joshua M</au><au>WONG, Terence Z</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Systematic Review of the Factors Affecting Accuracy of SUV Measurements</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>195</volume><issue>2</issue><spage>310</spage><epage>320</epage><pages>310-320</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><coden>AAJRDX</coden><abstract>There is growing interest in using PET/CT for evaluating early response to therapy in cancer treatment. Although widely available and convenient to use, standardized uptake value (SUV) measurements can be influenced by a variety of biologic and technologic factors. Many of these factors can be addressed with close attention to detail and appropriate quality control. This article will review factors potentially affecting SUV measurements and provide recommendations on ways to minimize when using serial PET to assess early response to therapy.
Scanner and reconstruction parameters can significantly affect SUV measurements. When using serial SUV measurements to assess early response to therapy, imaging should be performed on the same scanner using the same image acquisition and reconstruction protocols. In addition, attention to detail is required for accurate determination of the administered radiopharmaceutical dose.</abstract><cop>Reston, VA</cop><pub>American Roentgen Ray Society</pub><pmid>20651185</pmid><doi>10.2214/ajr.10.4923</doi><tpages>11</tpages></addata></record> |
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subjects | Algorithms Biological and medical sciences Fluorodeoxyglucose F18 - pharmacokinetics Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Investigative techniques, diagnostic techniques (general aspects) Medical sciences Models, Biological Neoplasms - diagnostic imaging Neoplasms - metabolism Positron-Emission Tomography - methods Radiopharmaceuticals - pharmacokinetics Reproducibility of Results Sensitivity and Specificity |
title | A Systematic Review of the Factors Affecting Accuracy of SUV Measurements |
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