Degradation studies of pentoxifylline: Isolation and characterization of a novel gem-dihydroperoxide derivative as major oxidative degradation product

Pentoxifylline was subjected to various stress conditions and degradation profile was studied with conventional LCMS. Interestingly, under oxidative stress conditions the drug substance underwent distinct transformation to give rise to a single major degradation product. The structure of this produc...

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Veröffentlicht in:Journal of pharmaceutical and biomedical analysis 2010-11, Vol.53 (3), p.335-342
Hauptverfasser: Mone, Mahesh Kumar, Chandrasekhar, K.B.
Format: Artikel
Sprache:eng
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